{"id":10455,"date":"2025-11-30T15:24:37","date_gmt":"2025-11-30T09:54:37","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=10455"},"modified":"2025-12-01T16:15:15","modified_gmt":"2025-12-01T10:45:15","slug":"what-is-thalassemia","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/what-is-thalassemia\/","title":{"rendered":"Thalassemia"},"content":{"rendered":"<h2><b>Thalassemia Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Scientists recently tested a gene-editing method called adenine base editing to fix two severe mutations that cause -thalassemia, a genetic blood disease.<\/span><\/p>\n<h2><b>About Thalassemia<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is an <\/span><b>inherited blood disorder.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It <\/span><b>affects<\/b><span style=\"font-weight: 400;\"> your <\/span><b>body\u2019s ability to produce normal hemoglobin.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><b>Hemoglobin <\/b><span style=\"font-weight: 400;\">is a <\/span><b>protein in red blood cells (RBCs).<\/b><span style=\"font-weight: 400;\"> It <\/span><b>allows your RBCs to transport oxygen<\/b><span style=\"font-weight: 400;\"> throughout your body.<\/span><\/li>\n<li style=\"text-align: justify;\"><b>If you have thalassemia<\/b><span style=\"font-weight: 400;\">, your <\/span><b>body produces fewer healthy hemoglobin<\/b><span style=\"font-weight: 400;\"> proteins, and your bone marrow <\/span><b>produces fewer healthy RBCs.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The<\/span><b> condition of having fewer RBCs<\/b><span style=\"font-weight: 400;\"> is called <\/span><b>anemia<\/b><span style=\"font-weight: 400;\">. That can make you feel tired and weak.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">As RBCs serve the vital role of delivering oxygen to tissues in your body, not having enough healthy RBCs can<\/span><b> deprive your body\u2019s cells of the oxygen they need to make energy<\/b><span style=\"font-weight: 400;\"> and thrive.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Thalassaemia is <\/span><b>caused by inheriting a gene mutation<\/b><span style=\"font-weight: 400;\"> (change in the normal DNA)<\/span><b> from one or both parents.<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Traits for thalassemia are <\/span><b>more common in people from Mediterranean countries<\/b><span style=\"font-weight: 400;\">, like <\/span><b>Greece and Turkey<\/b><span style=\"font-weight: 400;\">, and in people from <\/span><b>Asia, Africa, and the Middle East.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">There are <\/span><b>different types<\/b><span style=\"font-weight: 400;\"> of thalassemia. The type someone has depends on which gene mutation they inherit.<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Symptoms<\/b><span style=\"font-weight: 400;\">: Thalassemia can cause<\/span><b> mild or severe anemia<\/b><span style=\"font-weight: 400;\"> and other complications over time (such as<\/span><b> iron overload).<\/b><span style=\"font-weight: 400;\">\u00a0<\/span>\n<ul>\n<li style=\"text-align: justify;\"><b>Symptoms of Anemia Include:<\/b>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Fatigue.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Trouble breathing.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Feeling cold.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Dizziness.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Pale skin.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: justify;\"><b>Severe thalassemia may cause death.<\/b><\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: justify;\"><b>Treatments<\/b><span style=\"font-weight: 400;\">:<\/span>\n<ul>\n<li style=\"text-align: justify;\"><b>Blood transfusions <\/b><span style=\"font-weight: 400;\">\u2013 regular blood transfusions treat and prevent anaemia; in severe cases these are needed around once a month.<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Chelation therapy<\/b><span style=\"font-weight: 400;\"> \u2013 <\/span><b>treatment with medicine to remove the excess iron <\/b><span style=\"font-weight: 400;\">from the body that builds up as a result of having regular blood transfusions.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The <\/span><b>only possible cure <\/b><span style=\"font-weight: 400;\">for thalassemia is a <\/span><b>stem cell or bone marrow transplant, <\/b><span style=\"font-weight: 400;\">but this is not done very often because of the risks involved.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b>Source<\/b><span style=\"font-weight: 400;\">: <\/span><strong><a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/158997\/OPS\/G8SF83Q6D.1+GD5F84U1T.1.html\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thalassemia is an inherited blood disorder that affects your body\u2019s ability to produce normal hemoglobin. <\/p>\n","protected":false},"author":5,"featured_media":75957,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[21,3962,22,23],"class_list":{"0":"post-10455","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-prelims-pointers","9":"tag-thalassemia","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/10455","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=10455"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/10455\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/75957"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=10455"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=10455"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=10455"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}