{"id":105566,"date":"2026-05-28T15:03:25","date_gmt":"2026-05-28T09:33:25","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=105566"},"modified":"2026-05-28T16:35:21","modified_gmt":"2026-05-28T11:05:21","slug":"clear-technology","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/clear-technology\/","title":{"rendered":"CLEAR Technology"},"content":{"rendered":"<h2><b>CLEAR Technology Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Researchers at the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) recently developed a novel imaging platform called Cleavable Light-Erased Antibody Reporter (CLEAR).<\/span><\/p>\n<h2><b>About CLEAR Technology<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><b>Cleavable Light-Erased Antibody Reporter (CLEAR)<\/b><span style=\"font-weight: 400;\"> is a <\/span><b>novel imaging platform<\/b><span style=\"font-weight: 400;\"> that could significantly improve<\/span> <span style=\"font-weight: 400;\">the <\/span><b>visualization and mapping of proteins<\/b> <b>within biological samples.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It was <\/span><b>developed <\/b><span style=\"font-weight: 400;\">by researchers at the <\/span><b>Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR).<\/b><\/li>\n<li style=\"text-align: justify;\"><b>Researchers from the Indian Institute of Science also collaborated<\/b><span style=\"font-weight: 400;\"> in <\/span><b>demonstrating the technology <\/b><span style=\"font-weight: 400;\">in complex biological settings, particularly immune cell systems.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">CLEAR technology enables scientists to<\/span><b> visualize a large number of proteins within the same biological sample using a single fluorescent marker,<\/b><span style=\"font-weight: 400;\"> overcoming a major challenge in spatial protein mapping.\u00a0\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The scientists introduced a light-cleavable probe system that allows repeated cycles of protein labelling and imaging within the same spectral window.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><b>After imaging a set of proteins<\/b><span style=\"font-weight: 400;\">, the <\/span><b>fluorescent signal can be erased <\/b><span style=\"font-weight: 400;\">using a gentle pulse of 365 nm LED light, enabling researchers to <\/span><b>label and image a new set of proteins in the same cell.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It allows <\/span><b>increasingly detailed protein maps<\/b><span style=\"font-weight: 400;\"> to be generated across <\/span><b>specimens <\/b><span style=\"font-weight: 400;\">ranging <\/span><b>from single cells to complex tissue sections.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Unlike existing multiplex imaging methods, CLEAR combines<\/span><b> high multiplexing capability with speed, spatial resolution,<\/b><span style=\"font-weight: 400;\"> and compatibility with delicate<\/span><b> biological samples, including live cells.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The technology has the <\/span><b>potential to improve early disease detection<\/b><span style=\"font-weight: 400;\">, particularly in cancers and neurological disorders, while also helping researchers <\/span><b>better understand immune responses and cellular behaviour.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><b>In the long term<\/b><span style=\"font-weight: 400;\">, the platform could <\/span><b>contribute to precision medicine <\/b><span style=\"font-weight: 400;\">by enabling detailed molecular analysis that can support targeted therapies and personalized treatment approaches. <\/span><\/li>\n<\/ul>\n<p><strong>Source: <a href=\"https:\/\/ddnews.gov.in\/en\/scientists-develop-clear-technology-for-advanced-protein-imaging-in-cancer-research\/\" target=\"_blank\" rel=\"nofollow noopener\">DDN<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CLEAR Technology is a novel imaging platform that could significantly improve the visualization and mapping of proteins within biological samples. Read more about CLEAR Technology, Meaning, Uses, Latest News.<\/p>\n","protected":false},"author":23,"featured_media":105521,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[7798,21,22,23],"class_list":{"0":"post-105566","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-clear-technology","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/105566","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=105566"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/105566\/revisions"}],"predecessor-version":[{"id":105586,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/105566\/revisions\/105586"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/105521"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=105566"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=105566"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=105566"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}