{"id":119920,"date":"2026-08-19T12:53:36","date_gmt":"2026-08-19T07:23:36","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=119920"},"modified":"2026-08-19T12:53:36","modified_gmt":"2026-08-19T07:23:36","slug":"helicase","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/helicase\/","title":{"rendered":"Helicase"},"content":{"rendered":"<h2><b>Helicase Latest New<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">In a recent study scientists from the U.K. found that proteins Sld3-Sld7 detect &#8220;switched-on&#8221; MCM2-7 helicase and recruit Cdc45 to start DNA replication.<\/span><\/p>\n<h2><b>About Helicase<\/b><\/h2>\n<ul>\n<li><span style=\"font-weight: 400;\">Helicase is a <\/span><b>crucial enzyme<\/b><span style=\"font-weight: 400;\"> in molecular biology, playing an essential role in <\/span><b>DNA replication, repair, and transcription.\u00a0<\/b><\/li>\n<li><span style=\"font-weight: 400;\">It is a <\/span><b>motor protein<\/b><span style=\"font-weight: 400;\"> and unwinds <\/span><b>the double-stranded DNA (dsDNA) into single strands<\/b><span style=\"font-weight: 400;\">, so that the cell can copy the genetic information stored in them.<\/span><\/li>\n<li aria-level=\"1\"><b>Working of Helicase<\/b>\n<ul>\n<li><span style=\"font-weight: 400;\">First, the <\/span><b>enzyme attaches to a particular region of DNA<\/b><span style=\"font-weight: 400;\"> and moves along the molecule.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">It <\/span><b>uses energy from ATP<\/b><span style=\"font-weight: 400;\"> (the cell\u2019s main chemical energy source)\u00a0 to change its shape and force apart the two DNA strands.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">The result is a <\/span><b>Y-shaped region<\/b><span style=\"font-weight: 400;\"> called the replication fork, where the two strands are exposed<\/span><\/li>\n<li><span style=\"font-weight: 400;\">However, DNA tends to become increasingly twisted ahead of the replication fork as helicase moves along it.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Other <\/span><b>enzymes called topoisomerases<\/b><span style=\"font-weight: 400;\"> relieve this twisting and prevent the DNA from becoming tangled or breaking.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Once <\/span><b>helicase has separated the strands,<\/b><span style=\"font-weight: 400;\"> other replication machinery can use each exposed strand as a template to make a new complementary strand.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b>Source:<\/b> <strong><a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/200052\/OPS\/G06GDPB85.1+GUMGDPBN4.1.html\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Helicase is a crucial enzyme in molecular biology, playing an essential role in DNA replication, repair, and transcription. Read more about Helicase, Meaning, Working, Latest New.<\/p>\n","protected":false},"author":24,"featured_media":119902,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[9634],"class_list":["post-119920","post","type-post","status-publish","format-standard","has-post-thumbnail","category-upsc-prelims-current-affairs","tag-helicase","no-featured-image-padding"],"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/119920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=119920"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/119920\/revisions"}],"predecessor-version":[{"id":119948,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/119920\/revisions\/119948"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/119902"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=119920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=119920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=119920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}