{"id":122585,"date":"2026-09-03T12:30:17","date_gmt":"2026-09-03T07:00:17","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=122585"},"modified":"2026-09-03T12:30:17","modified_gmt":"2026-09-03T07:00:17","slug":"cold-allodynia","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/cold-allodynia\/","title":{"rendered":"Cold Allodynia"},"content":{"rendered":"<h2><b>Cold Allodynia Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">A team of researchers have identified the \u201cbrain circuit\u201d that involves the sensations associated with a certain side effect of chemotherapy known as \u201ccold allodynia\u201d.\u00a0<\/span><\/p>\n<h2><b>About Cold Allodynia<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>nerve-related pain condition<\/b><span style=\"font-weight: 400;\"> where even mild cold triggers intense burning or freezing sensations.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a condition in which the sufferer may feel pain or distress from even a regular level of cold temperatures.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Symptoms: <\/b>It includes <span style=\"font-weight: 400;\">sharp, burning pain, tingling, and pins-and-needles sensations.<\/span><\/li>\n<\/ul>\n<h2><b>Causes of Cold Allodynia\u00a0<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Diabetes<\/b><span style=\"font-weight: 400;\">: It can injure peripheral nerves, <\/span><b>leading to diabetic neuropathy<\/b><span style=\"font-weight: 400;\">, which may include cold allodynia.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Chemotherapy:<\/b><span style=\"font-weight: 400;\"> Certain cancer treatments affect nerve function and can cause painful cold sensitivity. Especially <strong>when oxaliplatin,<\/strong> a commonly used chemotherapy drug that contains platinum.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Infections:<\/b><span style=\"font-weight: 400;\"> Viral infections (e.g., shingles) can inflame nerves, sometimes causing persistent neuropathic pain.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Autoimmune Diseases:<\/b><span style=\"font-weight: 400;\"> Conditions like lupus or rheumatoid arthritis can target the nervous system.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Nutritional Deficiencies:<\/b><span style=\"font-weight: 400;\"> Lack of B vitamins, particularly <strong><a href=\"https:\/\/vajiramandravi.com\/current-affairs\/vitamin-b12\/\" target=\"_blank\">B12<\/a><\/strong>, can impair nerve health.<\/span><\/li>\n<\/ul>\n<h2><b>Treatments for Cold Allodynia\u00a0<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Medicines: Pregabalin, gabapentin, or duloxetine <\/b><span style=\"font-weight: 400;\">target nerve pain pathways.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Topical treatments<\/b><span style=\"font-weight: 400;\">: <\/span><b>Lidocaine or capsaicin<\/b><span style=\"font-weight: 400;\"> creams can desensitize skin receptors and Nonsteroidal anti-inflammatory drugs (NSAIDs) are also used.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Lifestyle Changes:<\/b><span style=\"font-weight: 400;\"> Keep feet warm, wear insulated socks and shoes. Use heated flooring pads or warm water soaks (avoid extremes of temperature).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Alternative Therapies: <\/b><span style=\"font-weight: 400;\">Transcutaneous electrical nerve stimulation (TENS) delivers mild electrical currents to block pain pathways.<\/span><\/li>\n<\/ul>\n<p><b>Source: <\/b><strong><a href=\"https:\/\/indianexpress.com\/article\/explained\/explained-sci-tech\/cold-allodynia-iisc-brain-circuit-chemotherapy-pain-10858970\/\" target=\"_blank\" rel=\"nofollow noopener\">IE<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cold Allodynia  is a nerve-related pain condition where even mild cold triggers intense burning or freezing sensations. Read more about Cold Allodynia, Causes, Symptoms, Latest News.<\/p>\n","protected":false},"author":24,"featured_media":122574,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[9977],"class_list":["post-122585","post","type-post","status-publish","format-standard","has-post-thumbnail","category-upsc-prelims-current-affairs","tag-cold-allodynia","no-featured-image-padding"],"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/122585","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=122585"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/122585\/revisions"}],"predecessor-version":[{"id":122599,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/122585\/revisions\/122599"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/122574"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=122585"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=122585"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=122585"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}