{"id":124176,"date":"2026-09-12T13:45:37","date_gmt":"2026-09-12T08:15:37","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=124176"},"modified":"2026-09-12T13:45:37","modified_gmt":"2026-09-12T08:15:37","slug":"proteome","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/proteome\/","title":{"rendered":"Proteome"},"content":{"rendered":"<h2><b>Proteome Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Proteomic signatures detectable in children may predict an increased risk for cardiovascular-kidney-metabolic disease (CKMD) in later life, offering a potential precision prevention approach to address cardiometabolic diseases at the earliest opportunity. <\/span><\/p>\n<h2><b>About Proteome<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">A proteome is a <\/span><b>set of proteins produced in an organism, system, or biological context.<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">We may refer to, for instance, the <\/span><b>proteome of a species<\/b><span style=\"font-weight: 400;\"> (for example, Homo sapiens) <\/span><b>or an organ<\/b><span style=\"font-weight: 400;\"> (for example, the liver).\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The proteome is <\/span><b>not constant;<\/b><span style=\"font-weight: 400;\"> it <\/span><b>differs from cell to cell <\/b><span style=\"font-weight: 400;\">and<\/span><b> changes over time.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The <\/span><b>proteome of any given individual<\/b><span style=\"font-weight: 400;\"> will be <\/span><b>unique<\/b><span style=\"font-weight: 400;\">, as protein expression patterns are <\/span><b>determined by an individual\u2019s genes.<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The proteome is always significantly <\/span><b>larger than the number of genes in an individual <\/b><span style=\"font-weight: 400;\">due to a number of factors:<\/span>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Gene sequences may be alternatively spliced following transcription to generate multiple protein variants from a single gene.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Proteins may be modified (e.g. glycosylated, phosphorylated, etc.) following translation to promote further variations.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: justify;\"><b>Proteomics <\/b><span style=\"font-weight: 400;\">is the large-scale <\/span><b>study of proteomes.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">With each protein playing distinct roles and functions, proteomics provides <\/span><b>valuable insights into cellular processes, signaling pathways,<\/b><span style=\"font-weight: 400;\"> and<\/span><b> disease mechanisms.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><b>Scientists typically study the proteome <\/b><span style=\"font-weight: 400;\">using techniques like <\/span><b>mass spectrometry <\/b><span style=\"font-weight: 400;\">or <\/span><b>traditional protein sequencing.<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Proteomics is <\/span><b>used to investigate:<\/b>\n<ul>\n<li style=\"text-align: justify;\"><b>when and where proteins are expressed<\/b><\/li>\n<li style=\"text-align: justify;\"><b>rates of protein production, degradation,<\/b><span style=\"font-weight: 400;\"> and steady-state abundance<\/span><\/li>\n<li style=\"text-align: justify;\"><b>how proteins are modified<\/b><span style=\"font-weight: 400;\"> (for example, post-translational modifications (PTMs) such as phosphorylation)<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">the <\/span><b>movement of proteins <\/b><span style=\"font-weight: 400;\">between subcellular compartments<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">the involvement of proteins in metabolic pathways<\/span><\/li>\n<li style=\"text-align: justify;\"><b>how proteins interact <\/b><span style=\"font-weight: 400;\">with one another<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Understanding the proteome can <\/span><b>shed light on disease mechanisms<\/b><span style=\"font-weight: 400;\">, <\/span><b>help identify potential drug target<\/b><span style=\"font-weight: 400;\">s, and develop novel therapeutic interventions. <\/span><\/li>\n<\/ul>\n<p><b>News: <\/b><a href=\"https:\/\/www.insideprecisionmedicine.com\/topics\/precision-medicine\/childhood-proteome-reveals-precision-prevention-approach-for-cardiometabolic-disease\/\" target=\"_blank\" rel=\"nofollow noopener\"><b>IPM<\/b><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Proteome is a set of proteins produced in an organism, system, or biological context. Read more about Proteome, Meaning, Examples, Usage, Latest News.<\/p>\n","protected":false},"author":23,"featured_media":124187,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[10203],"class_list":["post-124176","post","type-post","status-publish","format-standard","has-post-thumbnail","category-upsc-prelims-current-affairs","tag-proteome","no-featured-image-padding"],"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/124176","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=124176"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/124176\/revisions"}],"predecessor-version":[{"id":124201,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/124176\/revisions\/124201"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/124187"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=124176"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=124176"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=124176"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}