{"id":133091,"date":"2026-11-14T13:31:12","date_gmt":"2026-11-14T08:01:12","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=133091"},"modified":"2026-11-14T13:31:12","modified_gmt":"2026-11-14T08:01:12","slug":"pioxaniliprole","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/pioxaniliprole\/","title":{"rendered":"Pioxaniliprole: India\u2019s First Indigenous Insecticide Molecule, Mechanism of Action and Uses"},"content":{"rendered":"<h2><b>Pioxaniliprole\u00a0 Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">PI Industries Ltd\u2019s Pioxaniliprole has received approval from the Central Insecticides Board and Registration Committee (CIBRC).<\/span><\/p>\n<h2><b>About Pioxaniliprole<\/b><\/h2>\n<ul>\n<li><span style=\"font-weight: 400;\">It is India\u2019s first indigenously <\/span><b>discovered insecticide molecule.<\/b><\/li>\n<li><span style=\"font-weight: 400;\">It has been developed by PI Industries Ltd.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">It is an insecticidal active ingredient belonging to the <\/span><b>anthranilic diamide class of insecticides.<\/b><\/li>\n<li><b>Pioxaniliprole\u2019s Chemical Composition: <\/b><span style=\"font-weight: 400;\">It is a carboxamide compound containing <\/span><b>chlorine, nitrogen, oxygen and sulphur atoms.<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li><b>Mechanism of action<\/b><\/li>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><b>Target insect pests:<\/b><span style=\"font-weight: 400;\"> The insecticide is effective against <\/span><b>yellow stem borer, leaf folder<\/b><span style=\"font-weight: 400;\">, fall armyworm, tobacco cutworm, fruit borer and pod borer.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">It targets <\/span><b>ryanodine receptors<\/b><span style=\"font-weight: 400;\"> in insects, causing feeding cessation, muscle paralysis and eventually death.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">Pioxaniliprole acts by <\/span><b>targeting ryanodine receptors<\/b><span style=\"font-weight: 400;\"> (RyRs), specialised protein channels present in <\/span><b>insect muscle<\/b><span style=\"font-weight: 400;\"> cells that regulate the release of calcium ions from intracellular storage compartments into the cell cytoplasm.<\/span>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"3\"><span style=\"font-weight: 400;\">Calcium ions play a crucial role in normal muscle contraction and relaxation. Pioxaniliprole binds to and activates these receptors, triggering an uncontrolled release of calcium ions.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"2\"><span style=\"font-weight: 400;\">This disrupts normal muscle functioning in insects, leading to feeding cessation, lethargy, muscle paralysis and eventually death.<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><b>Source:<\/b> <strong><a href=\"https:\/\/indianexpress.com\/article\/upsc-current-affairs\/upsc-essentials\/knowledge-nugget-pioxaniliprole-approval-regulate-india-insecticides-10958674\/\" target=\"_blank\" rel=\"nofollow noopener\">IE<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pioxaniliprole is an insecticidal active ingredient belonging to the anthranilic diamide class of insecticides. Read more about Pioxaniliprole Insecticide, Developer, Significance, Latest News.<\/p>\n","protected":false},"author":24,"featured_media":133106,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[11489],"class_list":["post-133091","post","type-post","status-publish","format-standard","has-post-thumbnail","category-upsc-prelims-current-affairs","tag-pioxaniliprole","no-featured-image-padding"],"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/133091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=133091"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/133091\/revisions"}],"predecessor-version":[{"id":133099,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/133091\/revisions\/133099"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/133106"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=133091"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=133091"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=133091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}