{"id":14654,"date":"2023-08-29T03:55:59","date_gmt":"2023-08-28T22:25:59","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=14654"},"modified":"2025-04-02T22:06:20","modified_gmt":"2025-04-02T16:36:20","slug":"somatic-genetic-variants","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/somatic-genetic-variants\/","title":{"rendered":"Somatic genetic variants"},"content":{"rendered":"<h2><strong>About Somatic genetic variants:<\/strong><\/h2>\n<ul>\n<li>It is also known <strong>as somatic mutations<\/strong> which refer to alterations <strong>in the DNA sequence<\/strong> that occur in the cells of an individual\u2019s body after conception.<\/li>\n<li>Somatic genetic variants are important for a number of normal <strong>physiological processes<\/strong>. For example, the <strong>immune cells in our body<\/strong>, which produce antibodies, undergo an enormous amount of somatic changes to create diverse proteins.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3>Where do somatic mutations happen?<\/h3>\n<ul>\n<li>The change to a person\u2019s DNA during a somatic mutation happens after fertilization <strong>in any cell of their body that isn&#8217;t a sperm or egg cell (germ cells).<\/strong><\/li>\n<li>Cells continuously copy and replace themselves in humans.<\/li>\n<li>If a mutation occurs, all cells that form from that affected cell will have that mutation in its DNA.<\/li>\n<li>These mutations <strong>don\u2019t pass from parents to their children<\/strong> (not hereditary) and happen sporadically or randomly.<\/li>\n<li><strong>Common somatic mutation conditions include:<\/strong> Skin cancer, Lung Cancer, Sturge-Weber and syndrome etc<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3>Q1)\u00a0\u00a0What is DNA?<\/h3>\n<p>Deoxyribonucleic acid is a molecule that carries the genetic instructions used in the development, functioning, growth, and reproduction of all living organisms and many viruses. It is often referred to as the &#8220;blueprint of life&#8221; because it contains the information necessary for an organism&#8217;s structure and function.<\/p>\n<p><strong>Source:\u00a0<\/strong><a href=\"https:\/\/www.thehindu.com\/sci-tech\/science\/somatic-genetic-variants-tissue-turnover-cancer-development\/article67240857.ece\" target=\"_blank\" rel=\"nofollow noopener\"><u>Somatic genetic variants: A genomic revolution hiding inside our cells<\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Somatic genetic variants  refer to alterations in the DNA sequence that occur in the cells of an individual\u2019s body after conception.<\/p>\n","protected":false},"author":5,"featured_media":14655,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-14654","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/14654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=14654"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/14654\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/14655"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=14654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=14654"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=14654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}