{"id":1473,"date":"2024-12-25T12:13:04","date_gmt":"2024-12-25T12:13:04","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=167"},"modified":"2025-01-12T16:12:52","modified_gmt":"2025-01-12T10:42:52","slug":"hydroxychloroquine","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/hydroxychloroquine\/","title":{"rendered":"Hydroxychloroquine"},"content":{"rendered":"<h2><strong>Background of the Study:<\/strong><\/h2>\n<ul>\n<li>The controversial study by French researcher Didier Raoult, published on March 20, 2020, claimed that <strong>hydroxychloroquine (HCQ) and HCQ combined with azithromycin significantly reduced SARS-CoV-2 viral load<\/strong>.<\/li>\n<li>The paper was retracted on December 17, 2024, due to concerns about ethical approval and methodological issues.<\/li>\n<\/ul>\n<h2><strong>About Hydroxychloroquine (HCQ)<\/strong><\/h2>\n<ul>\n<li><strong>Hydroxychloroquine<\/strong> is a medication primarily used to treat <strong>malaria<\/strong>, <strong>rheumatoid arthritis<\/strong>, and <strong>systemic lupus erythematosus (SLE).<\/strong><\/li>\n<li>It reduces immune system activity or kills the malaria-causing parasites from <strong>Anopheles mosquito bites.<\/strong><\/li>\n<\/ul>\n<h2><strong>Use in Autoimmune Disorders:<\/strong><\/h2>\n<ul>\n<li>Effective in managing <strong>rheumatoid arthritis<\/strong> by reducing joint inflammation.<\/li>\n<li>Helps treat <strong>lupus<\/strong> by controlling the overactive immune response.<\/li>\n<\/ul>\n<h2><strong>HCQ and COVID-19:<\/strong><\/h2>\n<ul>\n<li>Early studies claimed HCQ could reduce SARS-CoV-2 viral loads, especially in combination with <strong>azithromycin<\/strong>.<\/li>\n<li>Proposed as a <strong>prophylactic<\/strong> to prevent COVID-19 infection; however, large-scale use raised concerns due to:\n<ul>\n<li><strong>Cardiac arrhythmia risks<\/strong><\/li>\n<li><strong>Liver damage<\/strong><\/li>\n<li>Potential weakening of the immune system\u2019s response to infection.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<hr \/>\n<h3>Q1: Is Hydroxychloroquine effective against COVID-19?<\/h3>\n<p>Hydroxychloroquine was initially studied as a potential treatment for COVID-19. However, subsequent research showed limited or no significant benefit, and its use for COVID-19 is not widely recommended by health authorities.<\/p>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/www.thehindu.com\/sci-tech\/science\/journal-finally-retracts-the-discredited-hydroxychloroquine-paper\/article69009649.ece\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The paper published in the International Journal of Antimicrobial Agents was withdrawn because of concerns about the ethical approval of the research.<\/p>\n","protected":false},"author":9,"featured_media":1507,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[31,21,22,23],"class_list":{"0":"post-1473","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-hydroxychloroquine","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/1473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=1473"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/1473\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/1507"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=1473"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=1473"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=1473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}