{"id":18280,"date":"2023-12-17T11:22:48","date_gmt":"2023-12-17T05:52:48","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=18280"},"modified":"2025-04-05T09:55:07","modified_gmt":"2025-04-05T04:25:07","slug":"ketamine","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/ketamine\/","title":{"rendered":"What is Ketamine?"},"content":{"rendered":"<h2>About Ketamine<\/h2>\n<ul>\n<li>Ketamine, also known as\u00a0Ketalar, is a medicine that doctors use to make people not feel pain during surgeries.<\/li>\n<li>It is derived from a\u00a0hallucinogenic drug Phencyclidine (PCP), it works by blocking the NMDA receptor in the brain and spinal cord, and increases a brain chemical or neurotransmitter called glutamate.<\/li>\n<li>It halts transmission of pain in the spinal cord and activates reward pathways of the brain.<\/li>\n<li>It is a dissociative anaesthetic with psychedelic properties is used under strict medical supervision for anaesthesia and to treat treatment-resistant depression.<\/li>\n<li>Ketamine therapy is used to\u00a0treat depression, anxiety, PTSD, end-of-life distress, chronic pain, drug\/alcohol problems, and more.<\/li>\n<li>Impact on the body\n<ul>\n<li>Ketamine induces\u00a0hallucinations, distorts sight and sound perceptions, leading to a sense of disconnection and loss of control.<\/li>\n<li>Potential side effects include agitation, depression, cognitive issues, unconsciousness, and memory loss.<\/li>\n<\/ul>\n<\/li>\n<li>It is a\u00a0Schedule X drug in India, which means it is tightly controlled and even monitored on a case-specific basis by the prescribing doctor.\u00a0<\/li>\n<\/ul>\n<h2>What are Schedule X drugs?<\/h2>\n<ul>\n<li>These are the \u2018restrictive drugs\u2019 which are covered under\u00a0the Drugs and Cosmetic Act and Rules. The list of Schedule X drugs includes over 536 drugs.<\/li>\n<li>The Schedule X drugs include\u00a0Narcotic and Psychotropic drugs which cause delusion, hallucination, psychosis, sedation and hypnosis.<\/li>\n<li>These drugs should be sold only on the prescription of a registered medication practitioner only.<\/li>\n<\/ul>\n<hr \/>\n<h3>Q1) What is The N-methyl-D-aspartate (NMDA) ?<\/h3>\n<p>It is a receptor of glutamate, the primary excitatory neurotransmitter in the human brain. It plays an integral role in synaptic plasticity, which is a neuronal mechanism believed to be the basis of memory formation.<\/p>\n<p><strong>Source: <\/strong><a href=\"https:\/\/indianexpress.com\/article\/health-wellness\/friends-actor-mathew-perry-died-of-ketamine-overdose-how-harmful-is-this-drug-9070677\/\" target=\"_blank\" rel=\"nofollow noopener\"><u>Friends actor Matthew Perry died of Ketamine overdose: How harmful is this drug? Here\u2019s all you need to know<\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ketamine, also known as Ketalar, is a medicine that doctors use to make people not feel pain during surgeries.<\/p>\n","protected":false},"author":5,"featured_media":18281,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-18280","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/18280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=18280"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/18280\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/18281"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=18280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=18280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=18280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}