{"id":21063,"date":"2025-06-25T14:38:28","date_gmt":"2025-06-25T09:08:28","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=21063"},"modified":"2025-06-25T15:46:39","modified_gmt":"2025-06-25T10:16:39","slug":"haemophilia-a","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/haemophilia-a\/","title":{"rendered":"Haemophilia A"},"content":{"rendered":"<h2 style=\"text-align: justify;\"><b>Haemophilia A Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">A simple and affordable point-of-care test kit has been indigenously developed by the National Institute of Immunohaematology for early diagnosis of genetic bleeding disorders haemophilia A and Von Willebrand Disease.<\/span><\/p>\n<h2 style=\"text-align: justify;\"><b>About Haemophilia A<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">It is a<\/span><b> hereditary bleeding disorder <\/b><span style=\"font-weight: 400;\">that happens when your <\/span><b>blood doesn\u2019t clot as well as it should<\/b><b>.<\/b><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Haemophilia A <\/b><b>Causes<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><b>When you bleed<\/b><span style=\"font-weight: 400;\">, a series of <\/span><b>reactions <\/b><span style=\"font-weight: 400;\">take place<\/span> <span style=\"font-weight: 400;\">in the body that <\/span><b>help blood clots form.<\/b><span style=\"font-weight: 400;\"> This process is called the <\/span><b>coagulation cascade.<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">It <\/span><b>involves <\/b><span style=\"font-weight: 400;\">as many as<\/span><b> 20 different special proteins<\/b><span style=\"font-weight: 400;\"> called coagulation, or <\/span><b>clotting, factors.\u00a0<\/b><\/li>\n<li><span style=\"font-weight: 400;\">You may have a higher chance of excess bleeding if one or more of these factors are missing or are not functioning like they should.<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Factor VIII (eight) is one such coagulation factor. <\/span><b>Hemophilia A is <\/b><span style=\"font-weight: 400;\">the <\/span><b>result of the body not making enough factor VIII.<\/b><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>How is Haemophilia A Passed On?<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">It is usually caused by an <\/span><b>altered gene<\/b><span style=\"font-weight: 400;\"> being <\/span><b>passed on to a child by their parents <\/b><span style=\"font-weight: 400;\">(inherited).<\/span><\/li>\n<li><b>Men <\/b><span style=\"font-weight: 400;\">with the altered gene <\/span><b>will have symptoms.<\/b><\/li>\n<li><b>Women <\/b><span style=\"font-weight: 400;\">with the altered gene (carriers) can have symptoms, but this is l<\/span><b>ess common, and the symptoms are less severe <\/b><span style=\"font-weight: 400;\">than in men.<\/span><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Haemophilia A <\/b><b>Symptoms<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">The severity of symptoms varies. <\/span><b>Prolonged bleeding <\/b><span style=\"font-weight: 400;\">is the <\/span><b>main symptom.<\/b><span style=\"font-weight: 400;\"> It is often <\/span><b>first seen when an infant is circumcised.<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li><b>Other bleeding problems<\/b><span style=\"font-weight: 400;\"> usually <\/span><b>show up when the infant starts crawling and walking.<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Mild cases may go unnoticed until later in life.\u00a0<\/span><\/li>\n<li><b>Symptoms <\/b><span style=\"font-weight: 400;\">may <\/span><b>first occur after surgery or injury<\/b><span style=\"font-weight: 400;\">. Internal bleeding may occur anywhere.<\/span><\/li>\n<li><b>Symptoms <\/b><span style=\"font-weight: 400;\">may include:<\/span>\n<ul>\n<li><b>Bleeding into joints<\/b><span style=\"font-weight: 400;\"> with associated <\/span><b>pain and swelling<\/b><\/li>\n<li><b>Blood in the urine<\/b><span style=\"font-weight: 400;\"> or stool<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Bruising<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Gastrointestinal tract and urinary tract bleeding<\/span><\/li>\n<li><b>Nosebleeds<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Prolonged bleeding from cuts, tooth extraction, and surgery<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Bleeding that starts without cause<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Haemophilia A <\/b><b>Treatment<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">Healthcare providers typically treat hemophilia A with <\/span><b>factor replacement therapy.\u00a0<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Healthcare providers will <\/span><b>inject concentrated factor VIII into your bloodstream.<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Factor VIII r<\/span><b>eplaces the missing blood protein<\/b><span style=\"font-weight: 400;\">, or factor, that helps blood to clot<\/span><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Key Facts about Von Willebrand Disease (VWD)<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">VWD is a <\/span><b>blood disorder<\/b><span style=\"font-weight: 400;\"> in which the <\/span><b>blood does not clot properly.\u00a0<\/b><\/li>\n<li><b>Cause<\/b><span style=\"font-weight: 400;\">: People with the disease have <\/span><b>low levels of von Willebrand factor,<\/b><span style=\"font-weight: 400;\"> a protein that helps blood clot, <\/span><b>or the protein doesn&#8217;t perform<\/b><span style=\"font-weight: 400;\"> as it should.<\/span><\/li>\n<li><b>Most people<\/b><span style=\"font-weight: 400;\"> with the disease are <\/span><b>born with it,<\/b><span style=\"font-weight: 400;\"> having <\/span><b>inherited it from one or both parents.\u00a0<\/b><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Von Willebrand Disease Symptoms<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">VWD <\/span><b>does not always cause symptoms<\/b> <b>unless<\/b><span style=\"font-weight: 400;\"> you have an <\/span><b>injury<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Sometimes it&#8217;s <\/span><b>found when you have more bleeding than usual after surgery <\/b><span style=\"font-weight: 400;\">or <\/span><b>giving birth.<\/b><\/li>\n<li><b>Symptoms <\/b><span style=\"font-weight: 400;\">of VWD can include:<\/span>\n<ul style=\"text-align: justify;\">\n<li><b>bruising easily<\/b><\/li>\n<li><span style=\"font-weight: 400;\">frequent <\/span><b>nosebleeds<\/b><\/li>\n<li><b>bleeding gums<\/b><\/li>\n<li><span style=\"font-weight: 400;\">bleeding more than usual after an injury or cut<\/span><\/li>\n<li><b>heavy periods<\/b><\/li>\n<\/ul>\n<\/li>\n<li><span style=\"font-weight: 400;\">Some people also have <\/span><b>more severe symptoms,<\/b><span style=\"font-weight: 400;\"> such as:<\/span>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">heavy bleeding that&#8217;s difficult to stop, for example, after an injury or procedure<\/span><\/li>\n<li><b>blood in your poo<\/b><\/li>\n<li><b>blood in your pee<\/b><span style=\"font-weight: 400;\"> (urine)<\/span><\/li>\n<li><span style=\"font-weight: 400;\">pain, swelling and stiffness in a joint<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Von Willebrand Disease <\/b><b>Treatment<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-weight: 400;\">VWD <\/span><b>can&#8217;t be cured.\u00a0<\/b><\/li>\n<li><b>But with treatment <\/b><span style=\"font-weight: 400;\">and self-care, most people with this disease <\/span><b>can lead active lives.<\/b><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><b>Source<\/b><span style=\"font-weight: 400;\">: <\/span><a href=\"https:\/\/economictimes.indiatimes.com\/industry\/healthcare\/biotech\/healthcare\/icmrs-niih-develops-simple-point-of-care-test-for-haemophilia-a-von-willebrand-disease\/articleshow\/122021443.cms?from=mdr\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">ET<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Haemophilia A is a genetic bleeding disorder where the blood doesn&#8217;t clot properly due to a deficiency of clotting factor VIII. Read more about Haemophilia A, Causes, Affects, Deficiency, Symptoms, Treatment, Latest News<\/p>\n","protected":false},"author":5,"featured_media":51780,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[1028,21,22,23],"class_list":{"0":"post-21063","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-haemophilia-a","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/21063","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=21063"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/21063\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/51780"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=21063"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=21063"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=21063"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}