{"id":23967,"date":"2025-04-27T02:52:26","date_gmt":"2025-04-26T21:22:26","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=23967"},"modified":"2025-10-14T17:13:58","modified_gmt":"2025-10-14T11:43:58","slug":"phenome-india-project","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/phenome-india-project\/","title":{"rendered":"&#8216;Phenome India&#8217; Project"},"content":{"rendered":"<h2>&#8216;Phenome India&#8217; Project Latest News<\/h2>\n<p>The Department of Biotechnology (DBT) had initiated a proposal call for &#8216;Translational Research using GenomeIndia data&#8217; without disclosing crucial information about the available phenotype data, causing concerns among researchers across India.<\/p>\n<h2>Background<\/h2>\n<ul>\n<li>The project successfully collected\u00a0<strong>blood samples<\/strong>\u00a0and\u00a0<strong>associated phenotype data<\/strong>\u00a0from over\u00a0<strong>20,000 individuals<\/strong>\u00a0belonging to\u00a0<strong>83 population groups<\/strong>, comprising\u00a0<strong>30 tribal<\/strong>\u00a0and\u00a0<strong>53 non-tribal<\/strong>\u00a0populations spread across India.<\/li>\n<li>Preliminary findings based on the genetic data of\u00a0<strong>9,772 individuals<\/strong>\u00a0were published in the journal\u00a0<strong>Nature Genetics<\/strong>\u00a0on\u00a0<strong>April 8, 2025<\/strong>.<\/li>\n<\/ul>\n<h3>Types of Phenotype Data Collected<\/h3>\n<ul>\n<li>The collected phenotype data included\u00a0<strong>anthropometric measurements<\/strong>\u00a0such as\u00a0<strong>height<\/strong>,\u00a0<strong>weight<\/strong>,\u00a0<strong>hip circumference<\/strong>,\u00a0<strong>waist circumference<\/strong>, and\u00a0<strong>blood pressure<\/strong>.<\/li>\n<li>From the blood samples,\u00a0<strong>complete blood counts<\/strong>\u00a0and\u00a0<strong>biochemical data<\/strong>\u00a0such as\u00a0<strong>glucose levels<\/strong>,\u00a0<strong>lipid profiles<\/strong>,\u00a0<strong>liver function<\/strong>, and\u00a0<strong>kidney function tests<\/strong>\u00a0were measured.<\/li>\n<\/ul>\n<h2>About &#8216;Phenome India&#8217; Project<\/h2>\n<ul>\n<li>The &#8220;Phenome India&#8221; project, officially named<strong>\u00a0Phenome India-CSIR Health Cohort Knowledgebase (PI-CheCK)<\/strong>\u00a0is an initiative launched by the\u00a0<strong>Council of Scientific and Industrial Research (CSIR)<\/strong>\u00a0on\u00a0<strong>December 7, 2023<\/strong>.<\/li>\n<li><strong>The main objective<\/strong>\u00a0of the project is to develop\u00a0<strong>India-specific risk prediction models<\/strong>\u00a0for\u00a0<strong>cardio-metabolic diseases<\/strong>\u00a0including\u00a0<strong>diabetes<\/strong>,\u00a0<strong>liver diseases<\/strong>, and\u00a0<strong>cardiac diseases<\/strong>.<\/li>\n<li>It is\u00a0<strong>India\u2019s first-ever pan-India longitudinal health monitoring study<\/strong>\u00a0focused specifically on cardio-metabolic health.<\/li>\n<li><strong>Participants<\/strong>\u00a0include around\u00a0<strong>10,000 individuals<\/strong>\u2014primarily\u00a0<strong>CSIR employees<\/strong>,\u00a0<strong>pensioners<\/strong>, and their\u00a0<strong>spouses<\/strong>\u2014from across\u00a0<strong>17 states<\/strong>\u00a0and\u00a0<strong>24 cities<\/strong>.<\/li>\n<li><strong>Collected data<\/strong>\u00a0includes\u00a0<strong>clinical questionnaires<\/strong>,\u00a0<strong>lifestyle and dietary habits<\/strong>,\u00a0<strong>anthropometric measurements<\/strong>,\u00a0<strong>imaging and scanning data<\/strong>, and\u00a0<strong>extensive biochemical and molecular data<\/strong>.<\/li>\n<li>This study is\u00a0<strong>crucial<\/strong>\u00a0for understanding how\u00a0<strong>ethnic diversity<\/strong>\u00a0and\u00a0<strong>lifestyle patterns<\/strong>\u00a0unique to India influence the\u00a0<strong>risk<\/strong>\u00a0and\u00a0<strong>incidence<\/strong>\u00a0of cardio-metabolic disorders.<\/li>\n<li>Through this project,\u00a0<strong>CSIR<\/strong>\u00a0is promoting a\u00a0<strong>Predictive, Personalised, Participatory, and Preventive (P4) healthcare model<\/strong>\u00a0suited to\u00a0<strong>Indian genetic and phenotypic profiles<\/strong>.<\/li>\n<\/ul>\n<h2>&#8216;Phenome India&#8217; Project FAQs<\/h2>\n<p><strong>Q1:\u00a0<\/strong>What is the GenomeIndia Project?<br \/>\n<strong>Ans:<\/strong>\u00a0The GenomeIndia Project is a national initiative to sequence the whole genomes of 10,000 Indian citizens to create a reference genome for the Indian population.<\/p>\n<p><strong>Q2:\u00a0<\/strong>Which institutions are leading the GenomeIndia Project?<br \/>\n<strong>Ans:<\/strong>\u00a0The project is coordinated by the Indian Institute of Science (IISc), Bengaluru, along with 20 other institutions across India.<\/p>\n<p><strong>Q3:\u00a0<\/strong>Under which ministry is the GenomeIndia Project initiated?<br \/>\n<strong>Ans:<\/strong>\u00a0The project is supported by the Department of Biotechnology (DBT), Ministry of Science and Technology, Government of India.<\/p>\n<p><strong>Source:\u00a0<\/strong><a href=\"https:\/\/www.thehindu.com\/sci-tech\/no-phenotype-data-details-in-genomeindias-proposal-call\/article69491916.ece#:~:text=While%20researchers%20from%2020%20institutions,%2C%E2%80%9D%20says%20Dr.%20Padmanaban\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Phenome India project (PI-CheCK) was launched by CSIR on December 7, 2023, to build a health cohort knowledgebase for research and innovation.<\/p>\n","protected":false},"author":5,"featured_media":48512,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[367],"class_list":{"0":"post-23967","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-phenome-india-project","9":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/23967","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=23967"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/23967\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/48512"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=23967"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=23967"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=23967"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}