{"id":25953,"date":"2025-11-08T07:29:13","date_gmt":"2025-11-08T01:59:13","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=25953"},"modified":"2025-11-10T15:24:18","modified_gmt":"2025-11-10T09:54:18","slug":"hayflick-limit","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/hayflick-limit\/","title":{"rendered":"Hayflick limit"},"content":{"rendered":"<h2><strong>About Hayflick limit:<\/strong><\/h2>\n<ul>\n<li>It refers to the maximum <strong>number of times a cell can divide<\/strong>.<\/li>\n<li>It&#8217;s named after scientist <strong>Leonard Hayflick,<\/strong> who discovered this phenomenon.<\/li>\n<li>The limit plays a crucial role in aging and the development of age-related diseases.<\/li>\n<li>Hayflick found that cells go <strong>through three phases.<\/strong>\n<ul>\n<li>The first is <strong>rapid, healthy cell division<\/strong>.<\/li>\n<li>In the second phase, mitosis slows. In the third stage, senescence, cells stop dividing entirely.<\/li>\n<li>They remain alive for a time after they stop dividing, but sometime after cellular division ends, cells do a particularly disturbing thing: Essentially, they commit suicide.<\/li>\n<li>Once a cell reaches the end of its life span, it undergoes a programmed cellular death <strong>called apoptosis.<\/strong><\/li>\n<\/ul>\n<\/li>\n<li>Hayflick\u2019s discovery got further weight after researchers in the 1970s discovered <strong>telomeres.<\/strong><\/li>\n<li>Telomeres <strong>are repetitive <\/strong><a href=\"https:\/\/vajiramandravi.com\/upsc-exam\/dna\/\" target=\"_blank\" rel=\"noopener noreferrer\" target=\"_blank\"><strong>DNA<\/strong><\/a><strong> sequences<\/strong> at the very end of these strands, meant to protect the chromosome.<\/li>\n<li>Crucially, with each cell division, these telomeres get slightly shorter. Eventually, the telomere loss reaches a critical point at which cell division ends.<\/li>\n<li>That said, while <strong>shortening telomeres<\/strong> is related to aging, the exact relationship between telomere length and lifespan remains unclear.\u00a0<\/li>\n<\/ul>\n<hr \/>\n<h3>Q1: What is Mitosis?<\/h3>\n<p>It is the process by which a cell replicates its chromosomes and then segregates them, producing two identical nuclei in preparation for cell division. Mitosis is generally followed by equal division of the cell&#8217;s content into two daughter cells that have identical genomes.<\/p>\n<p><strong>Source: <\/strong><a href=\"https:\/\/indianexpress.com\/article\/explained\/explained-sci-tech\/hayflick-limit-why-immortality-remains-out-of-humans-reach-9522701\/\" target=\"_blank\" rel=\"nofollow noopener\">Hayflick limit: Why immortality remains out of humans\u2019 reach<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Biomedical researcher Leonard Hayflick, who discovered that normal somatic cells can divide (and thus reproduce) only a certain number of times, died recently.<\/p>\n","protected":false},"author":5,"featured_media":25954,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-25953","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/25953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=25953"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/25953\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/25954"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=25953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=25953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=25953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}