{"id":26823,"date":"2024-09-24T10:19:29","date_gmt":"2024-09-24T04:49:29","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=26823"},"modified":"2025-10-10T13:22:02","modified_gmt":"2025-10-10T07:52:02","slug":"epigenetics","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/epigenetics\/","title":{"rendered":"What is Epigenetics?"},"content":{"rendered":"<h2><strong>About Epigenetics:<\/strong><\/h2>\n<ul>\n<li>Epigenetics is the <strong>study of how cells control gene activity without changing<\/strong> the <strong>DNA sequence.<\/strong><\/li>\n<li>&#8220;Epi-&#8220;means on or above in Greek, and &#8220;epigenetic&#8221; describes factors beyond the genetic code.\u00a0<\/li>\n<li><strong>Epigenetic changes are modifications to DNA<\/strong> that <strong>regulate whether genes are turned on or off.<\/strong><\/li>\n<li>These <strong>Epigenetic modifications <\/strong>are attached to DNA and <strong>do not change the sequence of DNA<\/strong> building blocks.\u00a0<\/li>\n<li>Within the complete set of <a href=\"https:\/\/vajiramandravi.com\/upsc-exam\/dna\/\" target=\"_blank\">DNA<\/a> in a cell (the genome), <strong>all of the modifications that regulate the activity<\/strong> (expression) <strong>of the genes<\/strong> is <strong>known as the epigenome<\/strong>.<\/li>\n<li>Because epigenetic changes help determine whether genes are turned on or off, they <strong>influence the production of proteins in cells<\/strong>.\n<ul>\n<li>This regulation helps <strong>ensure that each cell produces<\/strong> only <strong>proteins that are necessary<\/strong> for its function. For example, proteins that promote bone growth are not produced in muscle cells.\u00a0<\/li>\n<\/ul>\n<\/li>\n<li><strong>Patterns of epigenetic modification vary among individuals<\/strong>, in different tissues within an individual, and even in different cells within a tissue.<\/li>\n<li><strong>Environmental influences<\/strong>, such as a person\u2019s diet and exposure to pollutants, can <strong>impact the epigenome.<\/strong><\/li>\n<li><strong>Epigenetic modifications can be maintained from cell to cell as cells divide<\/strong> and, in some cases, <strong>can be inherited <\/strong>through the generations.<\/li>\n<li><strong>Errors in the epigenetic process<\/strong>, such as modification of the wrong gene or failure to add a chemical group to a particular gene or histone, <strong>can lead to abnormal gene activity or inactivity.<\/strong><\/li>\n<li><strong>Altered gene activity,<\/strong> including that caused by epigenetic errors, is a <strong>common cause of genetic disorders.<\/strong><\/li>\n<li>Conditions such as <strong>cancers, metabolic disorders, and degenerative disorders<\/strong> have been <strong>found to be related to epigenetic errors.<\/strong><\/li>\n<\/ul>\n<hr \/>\n<h3><strong>Q1<\/strong>: What is Deoxyribonucleic acid (DNA)?<\/h3>\n<p>DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person\u2019s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA). Mitochondria are structures within cells that convert the energy from food into a form that cells can use.<\/p>\n<p><strong>Source: <\/strong><a href=\"https:\/\/www.news-medical.net\/health\/Understanding-The-Role-of-Epigenetics-in-Human-Disease.aspx\" target=\"_blank\" rel=\"nofollow noopener\">The Role of Epigenetics in Human Disease<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Epigenetics is the study of how cells control gene activity without changing the DNA sequence.<\/p>\n","protected":false},"author":5,"featured_media":26824,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-26823","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/26823","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=26823"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/26823\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/26824"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=26823"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=26823"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=26823"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}