{"id":27113,"date":"2024-10-07T01:23:21","date_gmt":"2024-10-06T19:53:21","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=27113"},"modified":"2025-04-08T07:12:27","modified_gmt":"2025-04-08T01:42:27","slug":"progeria","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/progeria\/","title":{"rendered":"What is Progeria?"},"content":{"rendered":"<h2><strong>About Progeria:<\/strong><\/h2>\n<ul>\n<li>Progeria, also known as <strong>Hutchinson-Gilford progeria syndrom<\/strong>e, is an <strong>extremely rare<\/strong>, <strong>progressive genetic disorder<\/strong>.\u00a0<\/li>\n<li>It causes <strong>children to age rapidly<\/strong>.<\/li>\n<li>A tiny <strong>genetic mutation<\/strong> causes the disease.<\/li>\n<li>It is reported to occur in <strong>1 in 4 million newborns<\/strong> worldwide.\u00a0<\/li>\n<li>Newborns with the disorder <strong>appear to be healthy at birth<\/strong> but usually start to<strong> show<\/strong> signs of <strong>premature aging during<\/strong> their <strong>first one to two years of life<\/strong>.<\/li>\n<li>Their <strong>growth rate slows,<\/strong> and they <strong>don\u2019t gain weight as expected.<\/strong><\/li>\n<li>Progeria <strong>doesn&#8217;t affect a child&#8217;s intelligence<\/strong> or brain development.<\/li>\n<li>However, their rapid aging <strong>causes distinct physical characteristics<\/strong>, including:\n<ul>\n<li><strong>Hair loss<\/strong> (baldness).<\/li>\n<li>Prominent eyes.<\/li>\n<li><strong>Aged, wrinkled skin<\/strong>.<\/li>\n<li>A thin, <strong>beaked nose.<\/strong><\/li>\n<li><strong>Disproportionately small face<\/strong> compared to head size.<\/li>\n<li>Loss of fat under the skin.<\/li>\n<\/ul>\n<\/li>\n<li>As children with progeria get older, they <strong>get diseases<\/strong> you&#8217;d <strong>expect to see in people age 50 and older<\/strong>, including bone loss, hardening of the arteries, and heart disease.\u00a0<\/li>\n<li>The <strong>condition is always fatal<\/strong>. <strong>Heart problems or strokes<\/strong> are the <strong>eventual cause of death<\/strong> in most children with progeria.\u00a0<\/li>\n<li>The <strong>average life expectancy<\/strong> for a child with progeria is <strong>about 15 years<\/strong>. Some with the condition may die younger, and others may live longer, even to about 20 years.<\/li>\n<li>There&#8217;s <strong>no cure for progeria<\/strong>. A <strong>drug called lonafarnib<\/strong> has been shown to <strong>slow down the progression<\/strong> of the disease.<\/li>\n<\/ul>\n<hr \/>\n<h3><strong>Q1<\/strong>: What are genetic disorders?<\/h3>\n<p>Genetic disorders occur when a mutation (a harmful change to a gene, also known as a pathogenic variant) affects your genes or when you have the wrong amount of genetic material. Genes are made of DNA (deoxyribonucleic acid), which contain instructions for cell functioning and the characteristics that make you unique.<\/p>\n<p><strong>Source:<\/strong> <a href=\"https:\/\/timesofindia.indiatimes.com\/world\/europe\/survivor-of-rare-rapid-ageing-disease-progeria-dies-at-28\/articleshow\/113986054.cms\" target=\"_blank\" rel=\"nofollow noopener\">Survivor of rare rapid-ageing disease progeria dies at 28<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Progeria, also known as Hutchinson-Gilford progeria syndrome, is an extremely rare, progressive genetic disorder. <\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-27113","1":"post","2":"type-post","3":"status-publish","4":"format-standard","6":"category-upsc-prelims-current-affairs","7":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=27113"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27113\/revisions"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=27113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=27113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=27113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}