{"id":27553,"date":"2025-11-08T06:55:39","date_gmt":"2025-11-08T01:25:39","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=27553"},"modified":"2025-11-10T16:48:32","modified_gmt":"2025-11-10T11:18:32","slug":"nemaline-myopathy","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/nemaline-myopathy\/","title":{"rendered":"Nemaline Myopathy"},"content":{"rendered":"<h2><strong>About Nemaline Myopathy:<\/strong><\/h2>\n<ul>\n<li>It is a\u00a0<strong>rare genetic muscle<\/strong>\u00a0<strong>disorder<\/strong>\u00a0characterised by the presence of thread-like structures within muscle fibres affecting mobility and functionality.<\/li>\n<li>It is also known as\u00a0<strong>rod myopathy,<\/strong>\u00a0is a\u00a0<strong>rare congenital disorder<\/strong>\u00a0that weakens the skeletal muscles.<\/li>\n<li>This condition is hereditary, stemming from genetic mutations that impact muscle proteins.<\/li>\n<li>It is found in approximately 1 in every 50,000 births.<\/li>\n<li>The disorder can vary in severity, ranging from\u00a0<strong>mild cases with minimal impact<\/strong>\u00a0on daily life to\u00a0<strong>more severe forms<\/strong>\u00a0that lead to substantial muscle weakness, requiring significant medical intervention.<\/li>\n<li><strong>Symptoms<\/strong>\n<ul>\n<li>Muscle\u00a0<strong>weakness in the face, neck, and trunk<\/strong>, along with difficulties in feeding, breathing, and sometimes deformities.<\/li>\n<li>Affected individuals may also experience foot deformities, abnormal curvature of the spine (scoliosis), and joint deformities (contractures).<\/li>\n<\/ul>\n<\/li>\n<li><strong>Treatment:<\/strong>\u00a0There is\u00a0<strong>no cure for this<\/strong>\u00a0disease. Currently, treatment for nemaline myopathy is largely symptomatic and focuses on supportive care, including physiotherapy and muscle strengthening exercises.<\/li>\n<\/ul>\n<hr \/>\n<p>Q1: What is genetic mutation?<\/p>\n<p>It is a change to a gene&#8217;s\u00a0DNA sequence\u00a0to produce something different. It creates a permanent change to that gene&#8217;s DNA sequence. Genetic variations are important for humans to evolve, which is the process of change over generations.<\/p>\n<p><strong>News:<\/strong><a href=\"https:\/\/www.hindustantimes.com\/india-news\/cji-opens-up-about-foster-daughters-battle-with-nemaline-myopathy-what-is-this-rare-disorder-101729347257708.html\" target=\"_blank\" rel=\"nofollow noopener\">\u00a0CJI opens up about foster daughters&#8217; battle with nemaline myopathy. What is this rare disorder?<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nemaline Myopathy  is a rare genetic muscle disorder characterised by the presence of thread-like structures within muscle fibres affecting mobility and functionality.<\/p>\n","protected":false},"author":5,"featured_media":27554,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-27553","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27553","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=27553"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27553\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/27554"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=27553"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=27553"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=27553"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}