{"id":27801,"date":"2026-05-03T10:05:16","date_gmt":"2026-05-03T04:35:16","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=27801"},"modified":"2026-05-04T18:04:17","modified_gmt":"2026-05-04T12:34:17","slug":"spinal-muscular-atrophy","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/spinal-muscular-atrophy\/","title":{"rendered":"Spinal Muscular Atrophy"},"content":{"rendered":"<h2><b>Spinal Muscular Atrophy Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Recently, persons living with Spinal Muscular Atrophy (SMA), and parents have written to the Prime Minister of India seeking urgent intervention to ensure nationwide access to generic Risdiplam under the National Policy for Rare Diseases (NPRD).\u00a0<\/span><\/p>\n<h2><b>About Spinal Muscular Atrophy<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>rare and progressive neuromuscular disorder<\/b><span style=\"font-weight: 400;\"> that leads to muscle weakness and can cause life-threatening complications.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>debilitating genetic condition<\/b><span style=\"font-weight: 400;\"> which affects <\/span><b>motor neurons<\/b><span style=\"font-weight: 400;\"> that <\/span><b>control movement<\/b><span style=\"font-weight: 400;\">, and leads to progressive muscle weakening.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Cause:<\/b><span style=\"font-weight: 400;\"> Most forms of SMA are caused by <\/span><b>mutations of the survival motor neuron 1 gene<\/b><span style=\"font-weight: 400;\"> (SMN1) on the fifth chromosome, resulting in insufficient expression levels of the SMN protein.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Types of SMA:<\/b><span style=\"font-weight: 400;\"> There are five subtypes of <\/span><b>SMA- type 0, 1, 2, 3, 4.<\/b><span style=\"font-weight: 400;\"> Healthcare providers classify them <\/span><b>based on the age of onset,<\/b><span style=\"font-weight: 400;\"> as well as the severity and life expectancy.<\/span><\/li>\n<\/ul>\n<h2><b>Symptoms of Spinal Muscular Atrophy<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Its symptoms vary and may be mild or disabling, but <\/span><b>involve a weakness of the muscles that control movement.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The weakness in SMA tends to be more severe in the muscles that are close to the center of your body than in the muscles farther away from your body\u2019s center.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Treatment:<\/b><span style=\"font-weight: 400;\"> Unfortunately, <\/span><b>there isn\u2019t a cure for SMA.<\/b><span style=\"font-weight: 400;\"> Treatment for SMA mainly seeks to <\/span><b>manage symptoms<\/b><span style=\"font-weight: 400;\"> and prevent complications.<\/span><\/li>\n<\/ul>\n<p><b>Source:<\/b> <a href=\"https:\/\/www.thehindu.com\/sci-tech\/health\/access-to-generic-risdiplam-sought-under-policy-for-rare-diseases-for-people-with-spinal-muscular-atrophy\/article70931598.ece\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">TH<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Spinal Muscular Atrophy is a rare and progressive neuromuscular disorder that leads to muscle weakness and can cause life-threatening complications. <\/p>\n","protected":false},"author":5,"featured_media":101819,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[21,4515,350],"class_list":{"0":"post-27801","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-prelims-pointers","9":"tag-spinal-muscular-atrophy","10":"tag-upsc-prelims-current-afffairs","11":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27801","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=27801"}],"version-history":[{"count":2,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27801\/revisions"}],"predecessor-version":[{"id":101849,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/27801\/revisions\/101849"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/101819"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=27801"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=27801"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=27801"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}