{"id":29324,"date":"2026-01-02T12:39:50","date_gmt":"2026-01-02T07:09:50","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=29324"},"modified":"2026-01-02T15:38:24","modified_gmt":"2026-01-02T10:08:24","slug":"nimesulide","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/nimesulide\/","title":{"rendered":"Nimesulide"},"content":{"rendered":"<h2><b>Nimesulide Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">The government recently prohibited the manufacturing, sale and distribution of all oral formulations containing Nimesulide above 100 mg with immediate effect.<\/span><\/p>\n<h2><b>About Nimesulide<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">First <\/span><b>introduced in Italy in 1985,<\/b><span style=\"font-weight: 400;\"> it is a <\/span><b>non-steroidal anti-inflammatory drug (NSAID) <\/b><span style=\"font-weight: 400;\">used for its <\/span><b>pain-relieving, anti-inflammatory, and fever-reducing effects.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is commonly used to manage <\/span><b>acute pain, musculoskeletal disorders<\/b><span style=\"font-weight: 400;\">, dental pain, and symptoms associated with conditions such as osteoarthritis and dysmenorrhea.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nimesulide <\/span><b>works by inhibiting the action of cyclooxygenase (COX),<\/b><span style=\"font-weight: 400;\"> an <\/span><b>enzyme responsible<\/b><span style=\"font-weight: 400;\"> for the <\/span><b>production of prostaglandins-chemicals<\/b> <b>that cause pain, inflammation, and fever.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">By blocking this enzyme, Nimesulide reduces the levels of prostaglandins, thus providing relief from pain and inflammation.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">By targeting the underlying inflammatory process rather than just masking the pain, Nimesulide <\/span><b>helps relieve swelling, improves mobility and function in affected areas<\/b><span style=\"font-weight: 400;\">, and enhances overall comfort and quality of life.<\/span><\/li>\n<\/ul>\n<h2><b>Side Effects of Nimesulide<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Long-term usage may<\/span><b> harm the liver<\/b><span style=\"font-weight: 400;\"> or result in significant side effects, including <\/span><b>gastrointestinal bleeding or renal issues.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Apart from this, other side effects like<\/span><b> sour stomach, dizziness, skin infection, diarrhoea, and increased liver enzymes<\/b><span style=\"font-weight: 400;\"> might be observed in individuals.<\/span><\/li>\n<\/ul>\n<h2><b>Regulation<\/b><span style=\"font-weight: 400;\"><strong> of<\/strong> <\/span><b>Nimesulide<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">From its early years, nimesulide attracted safety concerns and was <\/span><b>never approved for use<\/b><span style=\"font-weight: 400;\"> in countries including the <\/span><b>United States, the UK, Canada, Australia, New Zealand, and Japan.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>In 2008, the International Society of Drug Bulletins<\/b><span style=\"font-weight: 400;\">, a WHO-supported network, <\/span><b>called for a global ban on nimesulide.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>India banned <\/b><span style=\"font-weight: 400;\">the use of<\/span><b> nimesulide in children below 12 years of age in 2011 <\/b><span style=\"font-weight: 400;\">but <\/span><b>continued to allow its use in older patients.<\/b><span style=\"font-weight: 400;\"> However, concerns have persisted.<\/span><\/li>\n<\/ul>\n<p><b>Source: <\/b><strong><a href=\"https:\/\/www.newsonair.gov.in\/govt-bans-manufacturing-sale-and-distribution-of-oral-drug-nimesulide-above-100-mg\/#:~:text=Nimesulide%20is%20a%20nonsteroidal%20antiinflammatory,No%20posts%20found\" target=\"_blank\" rel=\"nofollow noopener\">News On Air<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) is widely used to relieve pain and inflammation. Read more about Nimesulide, Uses, Side Effects, Regulation, Latest News.<\/p>\n","protected":false},"author":5,"featured_media":80558,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[4507],"class_list":{"0":"post-29324","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-nimesulide","9":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/29324","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=29324"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/29324\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/80558"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=29324"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=29324"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=29324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}