{"id":34772,"date":"2022-11-13T12:43:25","date_gmt":"2022-11-13T07:13:25","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=34772"},"modified":"2025-04-20T17:07:18","modified_gmt":"2025-04-20T11:37:18","slug":"desi-antibiotic-under-trial-in-europe-saves-womans-life","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/desi-antibiotic-under-trial-in-europe-saves-womans-life\/","title":{"rendered":"Desi Antibiotic Under Trial in Europe Saves Woman\u2019s Life"},"content":{"rendered":"<h3><strong>What\u2019s in today\u2019s article:<\/strong><\/h3>\n<ul>\n<li><strong>About antimicrobial resistance<\/strong><\/li>\n<li><strong>News Summary<\/strong><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><strong>Why in news?<\/strong><\/h3>\n<ul>\n<li>The World Health Organisation (WHO) has identified WCK5222, a made in India medicine currently undergoing clinical trials in various European countries, as a promising antibiotic under investigation.<\/li>\n<li>Developed by Aurangabad based Wockhardt Research Centre, the drug has recently saved the life of a Nepali national infected with Pseudomonas aeruginosa &#8211; a gram-negative bacteria resistant to all antibiotics.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><strong>Antimicrobial resistance (AMR):<\/strong><\/h2>\n<ul>\n<li><strong>Background:\u00a0<\/strong>Antimicrobials &#8211; including antibiotics, antivirals, antifungals and antiparasitics &#8211; are medicines used to prevent and treat infections in humans, animals and plants.<\/li>\n<li><strong>About AMR:<\/strong>\n<ul>\n<li>AMR occurs when bacteria, viruses, fungi and parasites change over time and\u00a0<strong>no longer respond to medicines<\/strong>\u00a0(develops drug resistance).<\/li>\n<li>This makes infections increasingly difficult or impossible to treat,\u00a0increasing the risk of disease spread, severe illness and death.<\/li>\n<li>They can<strong>\u00a0spread from person to person<\/strong>\u00a0or between people and animals, including from food of animal origin.<\/li>\n<li>The rapid global spread of multi and pan-drug resistant bacteria &#8211; &#8220;<strong>superbugs,<\/strong>&#8221; is particularly concerning.<\/li>\n<li>As a result, WHO recently identified AMR as<strong>\u00a0a major public health threat.<\/strong>\n<ul>\n<li>This is a major concern because a resistant infection may kill, can spread to others, and imposes huge costs to individuals and society.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li><strong>The main drivers of AMR include:<\/strong>\n<ul>\n<li>The misuse and overuse of antimicrobials;<\/li>\n<li>Lack of access to clean water, sanitation and hygiene (WASH) for both humans and animals;<\/li>\n<li>Poor infection and disease prevention and control in health-care facilities and farms;<\/li>\n<li>Poor access to quality, affordable medicines, vaccines and diagnostics;<\/li>\n<li>Lack of awareness and knowledge; and<\/li>\n<li>Lack of enforcement of legislation.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Measures taken to address challenges posed by anti-microbial resistance (AMR) in India<\/strong>\n<ul>\n<li><strong>AMR surveillance network<\/strong>\u00a0has been strengthened by establishing labs in State Medical College.<\/li>\n<li><strong>National action plan on containment of Antimicrobial Resistance (NAP-AMR)<\/strong>\u00a0focusing on One Health approach was launched in April 2017 with the aim of involving various stakeholder ministries\/departments.<\/li>\n<li><strong>Delhi Declaration on AMR<\/strong>\u2013 an inter-ministerial consensus was signed by the ministers of the concerned ministries pledging their support in AMR containment.<\/li>\n<li><strong>AMR Research &amp; International Collaboration<\/strong>: ICMR has taken initiatives to develop new drugs \/medicines through international collaborations in order to strengthen medical research in AMR.<\/li>\n<li>Government of India has taken following initiatives to increase awareness about antibiotics misuse:\n<ul>\n<li>ICMR has initiated antibiotic stewardship program (AMSP) to control misuse and overuse of antibiotics in hospital wards and ICUs.<\/li>\n<li>DCGI has banned 40 fixed dose combinations (FDCs) which were found inappropriate.<\/li>\n<li>Various IEC activities like public conclave, poster and quiz competitions have been conducted by National Centre for Disease Control.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><strong>News Summary:<\/strong><\/h2>\n<p><img decoding=\"async\" src=\"https:\/\/vajiramandravi.s3.us-east-1.amazonaws.com\/media\/editor_images\/2022\/11\/13\/12\/53\/56\/63709b8c88f5c905b4aba7f9_OI.PNG\" alt=\"\" \/><\/p>\n<ul>\n<li>Antibiotic or antimicrobial resistance is\u00a0<strong>on the rise in India<\/strong>, where antibiotics are frequently self-administered or prescribed by pharmacies.<\/li>\n<li>Resistance level is increasing by\u00a0<strong>5% to 10%<\/strong>\u00a0every year for broad-spectrum antimicrobials.<\/li>\n<li>Multi-drug resistance is common in infections with gram-negative bacterias such as Acinetobacter baumanii and Pseudomonas aeruginosa in India.<\/li>\n<li>The 6th detailed report on AMR trends published by the Indian Council for Medical Research (ICMR) revealed that carbapenem, a strong antibiotic used to treat pneumonia and septicemia, is no longer beneficial to many ICU patients.<\/li>\n<li><strong>New treatment alternatives<\/strong>\u00a0for multi or extremely drug-resistant pathogens are urgently needed.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Desi antibiotic under trial in Europe save womans life,WHO has identified WCK5222,made in India medicine<\/p>\n","protected":false},"author":5,"featured_media":34773,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[18],"tags":[],"class_list":{"0":"post-34772","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-mains-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/34772","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=34772"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/34772\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/34773"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=34772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=34772"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=34772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}