{"id":4166,"date":"2023-03-12T02:04:36","date_gmt":"2023-03-11T20:34:36","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=4166"},"modified":"2025-03-26T22:14:46","modified_gmt":"2025-03-26T16:44:46","slug":"what-is-iitr00693","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/what-is-iitr00693\/","title":{"rendered":"What is IITR00693?"},"content":{"rendered":"<h2><strong>About IITR00693:<\/strong><\/h2>\n<ul>\n<li>It is a novel <strong>antibacterial small molecule.<\/strong><\/li>\n<li>It has shown potent antibacterial activity <strong>against a wide range of Gram-positive and Gram-negative bacteria<\/strong>, <strong>including<\/strong> some of the most problematic <strong>drug-resistant strains<\/strong>.<\/li>\n<li>IITR00693 <strong>acts like a dual sword<\/strong>; it not only <strong>strikes down the most stubborn bacteria<\/strong> but also <strong>prevents the emergence of resistance<\/strong>, ensuring that it remains effective for generations to come.<\/li>\n<li>It <strong>enhances the activity of antibiotics<\/strong> that are used in the treatment of bacterial infections.<\/li>\n<li>It <strong>potentiates the activity of polymyxins<\/strong> <strong>against<\/strong> two notorious <strong>multidrug-resistant<\/strong> skin-infecting <strong>pathogens<\/strong>, Staphylococcus aureus, and Pseudomonas aeruginosa.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><strong>What are Gram-positive and Gram-negative bacteria?<\/strong><\/h3>\n<ul>\n<li><strong>Gram-positive bacteria:<\/strong>\n<ul>\n<li>They show <strong>blue or purple after gram-staining<\/strong> in a laboratory test.<\/li>\n<li>They have <strong>thick peptidoglycan cell walls<\/strong>.<\/li>\n<li>They <strong>do not have a protective outer membrane<\/strong>.<\/li>\n<\/ul>\n<\/li>\n<li><strong>Gram-negative bacteria:<\/strong>\n<ul>\n<li>They show <strong>pink or red on staining<\/strong>.<\/li>\n<li>They have <strong>thin peptidoglycan cell walls<\/strong>.<\/li>\n<li>They <strong>have an outer membrane.\u00a0\u00a0<\/strong><\/li>\n<li><strong>They release different toxins and affect the body <\/strong>in different ways.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3><strong>Q1)\u00a0What are antibiotics?<\/strong><\/h3>\n<p>Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.<\/p>\n<p><strong>Source:\u00a0<\/strong><a href=\"https:\/\/timesofindia.indiatimes.com\/city\/dehradun\/research-team-at-iit-roorkee-discovers-new-antibacterial-molecule\/articleshow\/98573909.cms\" target=\"_blank\" rel=\"nofollow noopener\"><u>Research team at IIT-Roorkee discovers new antibacterial molecule<\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>IITR00693 is a novel antibacterial small molecule.<\/p>\n","protected":false},"author":5,"featured_media":4167,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-4166","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/4166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=4166"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/4166\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/4167"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=4166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=4166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=4166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}