{"id":5268,"date":"2022-12-30T03:00:14","date_gmt":"2022-12-29T21:30:14","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=5268"},"modified":"2025-03-27T05:17:25","modified_gmt":"2025-03-26T23:47:25","slug":"what-is-haemophilia","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/what-is-haemophilia\/","title":{"rendered":"What is Haemophilia?"},"content":{"rendered":"<h2><strong>Why in news?<\/strong><\/h2>\n<ul>\n<li>Data from the study showed that a single dose of the therapy was superior to the current standard of care in helping reduce the bleeding rate in patients with moderately severe to severe forms of haemophilia B.<\/li>\n<\/ul>\n<h3><strong>What is Haemophilia?<\/strong><\/h3>\n<ul>\n<li>It is a medical condition, <strong>mostly inherited<\/strong>, in which the ability of blood to clot is severely reduced.\u00a0<\/li>\n<li>This disease is caused by <strong>a mutation in one of the genes, <\/strong>that provides instructions for making the clotting factor proteins needed to form a blood clot.<\/li>\n<li>This change or mutation can prevent the clotting protein from working properly or to be missing altogether. These genes are located on <strong>the X chromosome<\/strong>.<\/li>\n<li>Men are more vulnerable to haemophilia than women. It is a rare disease where in about 1 in 10,000 people are born with it.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr \/>\n<p>Q1) What are the types of haemophilia?<\/p>\n<p>The main types of haemophilia include-\u00a0Haemophilia A which happens because of the deficiency of clotting factor 8, Haemophilia B which happens because of the deficiency of clotting factor 9 and Haemophilia C, also known as Rosenthal syndrome occurs due to the deficiency of factor 11.<\/p>\n<p><strong>Source:\u00a0<\/strong><a href=\"https:\/\/www.thehindu.com\/sci-tech\/health\/pfizers-haemophilia-b-gene-therapy-succeeds-in-late-stage-study\/article66317171.ece\" target=\"_blank\" rel=\"nofollow noopener\"><u>Pfizer&#8217;s haemophilia B gene therapy succeeds in late-stage study<\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Haemophilia is a medical condition, mostly inherited, in which the ability of blood to clot is severely reduced.<\/p>\n","protected":false},"author":5,"featured_media":5269,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-5268","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/5268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=5268"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/5268\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/5269"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=5268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=5268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=5268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}