{"id":53091,"date":"2025-07-02T14:02:54","date_gmt":"2025-07-02T08:32:54","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=53091"},"modified":"2025-07-02T14:02:54","modified_gmt":"2025-07-02T08:32:54","slug":"microcrystalline-cellulose","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/microcrystalline-cellulose\/","title":{"rendered":"Microcrystalline Cellulose (MCC)"},"content":{"rendered":"<h2 style=\"text-align: justify;\"><b>Microcrystalline Cellulose Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The pharma unit of Sigachi Industries in Hyderabad, which makes microcrystalline cellulose (MCC), was the scene of a lethal accident recently, with the toll rising to 36.<\/span><\/p>\n<h2 style=\"text-align: justify;\"><b>About Microcrystalline Cellulose<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is a <\/span><b>free-flowing powdery substance extracted as a pulp from fibrous plant material <\/b><span style=\"font-weight: 400;\">called refined wood pulp.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is a<\/span><b> purified, partially depolymerized cellulose<\/b><span style=\"font-weight: 400;\"> having the <\/span><b>formula (C6H10O5)n<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Chemically<\/b><span style=\"font-weight: 400;\">, it is an <\/span><b>inert substance<\/b><span style=\"font-weight: 400;\">, is not degraded during digestion, and has no appreciable absorption.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">As a<\/span><b> natural, fiber-rich<\/b><span style=\"font-weight: 400;\"> component, it\u2019s <\/span><b>nontoxic and chewable.<\/b><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Wood is the most common source <\/b><span style=\"font-weight: 400;\">of pharmaceutical MCC, in which <\/span><b>cellulose chains<\/b><span style=\"font-weight: 400;\"> are closely packed in layered form and are <\/span><b>held together by a cross-linking polymer<\/b><span style=\"font-weight: 400;\"> and <\/span><b>strong hydrogen bonds.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><b>Its crystalline structure<\/b><span style=\"font-weight: 400;\"> is <\/span><b>due to <\/b><span style=\"font-weight: 400;\">its microfibres having a<\/span><b> high degree of three-dimensional internal bonding.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><b>During compression, MCC plastically deforms, <\/b><span style=\"font-weight: 400;\">and therefore, <\/span><b>interparticle bonding increases.<\/b><span style=\"font-weight: 400;\"> The <\/span><b>plasticity <\/b><span style=\"font-weight: 400;\">of the MCC is the<\/span><b> main reason for its exceptional binding property.<\/b><\/li>\n<\/ul>\n<h2 style=\"text-align: justify;\"><b>Microcrystalline Cellulose <\/b><b>Applications<\/b><\/h2>\n<ul style=\"text-align: justify;\">\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is used as a <\/span><b>texturizer, extender, emulsifier, and binder in the pharmaceutical industry<\/b><span style=\"font-weight: 400;\"> and as a <\/span><b>bulking agent in food production.\u00a0<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Its vital use is in the <\/span><b>making of vitamin supplements and tablets.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">MCC can <\/span><b>add weight to a drug and facilitate the active ingredients to function effectively<\/b><span style=\"font-weight: 400;\"> while making the drug conform to weight specifications.<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><strong>Source: <a href=\"https:\/\/epaper.thehindu.com\/ccidist-ws\/th\/th_delhi\/issues\/137979\/OPS\/GHTEJ0O5E.1+G8NEJ2KKD.1.html\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microcrystalline Cellulose is a free-flowing powdery substance extracted as a pulp from fibrous plant material called refined wood pulp.<\/p>\n","protected":false},"author":23,"featured_media":53190,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[1298,21,23],"class_list":{"0":"post-53091","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-microcrystalline-cellulose","9":"tag-prelims-pointers","10":"tag-upsc-prelims-current-affairs","11":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/53091","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=53091"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/53091\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/53190"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=53091"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=53091"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=53091"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}