{"id":53393,"date":"2025-07-04T12:00:32","date_gmt":"2025-07-04T06:30:32","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=53393"},"modified":"2025-07-04T15:14:46","modified_gmt":"2025-07-04T09:44:46","slug":"dengiall","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/dengiall\/","title":{"rendered":"DengiAll"},"content":{"rendered":"<h2><b>DengiAll Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">India has reached the 50 per cent enrolment mark in its first phase III clinical trial for the indigenous tetravalent dengue vaccine, DengiAll.<\/span><\/p>\n<h2><b>About DengiAll<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is developed by <\/span><b>Panacea Biotec Limited<\/b><span style=\"font-weight: 400;\"> under a licensing agreement with the <\/span><b>National Institutes of Health (NIH).<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">has a weakened form of all four dengue virus subtypes and has the same virus composition as the vaccine developed by NIH, except for the inactive ingredients.\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A Phase I and II clinical trial conducted in India revealed a balanced and robust immune response across all four dengue virus types. The vaccine was also found to be safe and well-tolerated.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Multiple ICMR institutes are involved in the study to evaluate the efficacy, immunogenicity and safety of DengiAll. The <\/span><b>ICMR-National Institute of Translational Virology (NITVAR) and AIDS Research<\/b><span style=\"font-weight: 400;\"> (formerly ICMR-NARI) is responsible for overall trial coordination.<\/span><\/li>\n<\/ul>\n<h3><b>Key Facts about Dengue<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>mosquito-borne viral infection.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is more common in <\/span><b>tropical and subtropical climates,<\/b><span style=\"font-weight: 400;\"> mostly in urban and semi-urban areas.<\/span><\/li>\n<\/ul>\n<h3><b>Transmission of Dengue<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is transmitted to humans through the <\/span><b>bite of infected Aedes mosquitos<\/b><span style=\"font-weight: 400;\"> carrying one of four types of dengue virus (DENV).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Dengue <\/span><b>isn\u2019t contagious from person to person<\/b><span style=\"font-weight: 400;\"> except when passed from a pregnant person to their child.<\/span><\/li>\n<\/ul>\n<h3><b>Symptoms of Dengue<\/b><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The most common symptoms are high fever, headache, body aches, nausea, and rash. Most will get better in 1\u20132 weeks.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">A very small portion of people with dengue fever get a severe case. It\u2019s called dengue hemorrhagic fever.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Treatment: <\/b><span style=\"font-weight: 400;\">There is <\/span><b>no specific medicine to treat dengue<\/b><span style=\"font-weight: 400;\">. The focus is on treating pain symptoms.<\/span><\/li>\n<\/ul>\n<p><b>Source:<\/b> <a href=\"https:\/\/indianexpress.com\/article\/health-wellness\/indias-first-phase-3-dengue-vaccine-trial-hits-50-enrolment-mark-10101785\/\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">IE<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>DengiAll is developed by Panacea Biotec Limited under a licensing agreement with the National Institutes of Health (NIH). Read more about DengiAll, Facts, Transmission, Symptoms, Treatment, Latest News<\/p>\n","protected":false},"author":24,"featured_media":53399,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[1332,21,22,23],"class_list":{"0":"post-53393","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-dengiall","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/53393","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/24"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=53393"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/53393\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/53399"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=53393"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=53393"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=53393"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}