{"id":65487,"date":"2025-09-28T16:51:10","date_gmt":"2025-09-28T11:21:10","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=65487"},"modified":"2025-09-29T17:27:57","modified_gmt":"2025-09-29T11:57:57","slug":"ethambutol-hydrochloride","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/ethambutol-hydrochloride\/","title":{"rendered":"Ethambutol Hydrochloride"},"content":{"rendered":"<h2><b>Ethambutol Hydrochloride Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">India recently launched an anti-dumping investigation on imports of tuberculosis drug Ethambutol Hydrochloride from China and Thailand.<\/span><\/p>\n<h2><b>About Ethambutol Hydrochloride<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is an <\/span><b>antibacterial prescription medicine<\/b><span style=\"font-weight: 400;\"> used for the treatment of <\/span><b>tuberculosis (TB).<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is a <\/span><b>synthetic<\/b><span style=\"font-weight: 400;\">, <\/span><b>water soluble, heat stable<\/b><span style=\"font-weight: 400;\"> compound.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is specifically <\/span><b>effective against actively growing microorganisms of the genus Mycobacterium<\/b><span style=\"font-weight: 400;\"> including <\/span><b>M. tuberculosis.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is used to combat both pulmonary and extrapulmonary tuberculosis.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Mechanism:<\/b>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Ethambutol (HCl) specifically<\/span><b> targets the synthesis of the cell wall in M. tuberculosis.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">By interfering with the polymerization of arabinogalactan, a key component of the mycobacterial cell wall, Ethambutol <\/span><b>disrupts the structural integrity of the bacteria,<\/b><span style=\"font-weight: 400;\"> leading to its demise.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Its unique mode of action is <\/span><b>fundamental in combination therapies, <\/b><span style=\"font-weight: 400;\">where it is often used in conjunction with other anti-tubercular drugs to prevent resistance and enhance efficacy.<\/span><\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align: justify;\"><b>Resistance to ethambutol emerges rapidly when the drug is used alone.<\/b><span style=\"font-weight: 400;\"> Therefore <\/span><b>ethambutol<\/b><span style=\"font-weight: 400;\"> is <\/span><b>always given in combination with other antituberculosis drugs.<\/b><\/li>\n<\/ul>\n<p><b>Source<\/b><span style=\"font-weight: 400;\">: <\/span><a href=\"https:\/\/www.thehindu.com\/business\/anti-dumping-probe-opened-on-tb-drug-ethambutol-hydrochloride\/article70102751.ece\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">TH<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ethambutol Hydrochloride is an antibacterial prescription medicine used for the treatment of tuberculosis (TB). <\/p>\n","protected":false},"author":23,"featured_media":65719,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[2953,21,22,23],"class_list":{"0":"post-65487","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-ethambutol-hydrochloride","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/65487","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=65487"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/65487\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/65719"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=65487"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=65487"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=65487"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}