{"id":8787,"date":"2022-10-30T01:35:02","date_gmt":"2022-10-29T20:05:02","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=8787"},"modified":"2025-03-29T09:06:18","modified_gmt":"2025-03-29T03:36:18","slug":"salmonella-tphimurium-dt104","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/salmonella-tphimurium-dt104\/","title":{"rendered":"Salmonella Tphimurium DT104"},"content":{"rendered":"<h2><strong>About Salmonella Tphimurium DT104:<\/strong><\/h2>\n<ul>\n<li>The rapid and unselective use of traditional antibiotics gives rise to the emergence of drug resistant phenotype in typhoidal and non-typhoidal Salmonella serovars.<\/li>\n<li>It has increased the difficulties in curing Salmonella-induced food-borne illnesses (majorly typhoid or paratyphoid fever, gastroenteritis, and diarrhoea) worldwide.<\/li>\n<li><strong>Salmonella typhimurium ST313<\/strong>\u00a0is an invasive non-typhoidal Salmonella serovar, causes bloodstream infection in the malnourished and immunocompromised population of sub-Saharan Africa.<\/li>\n<li>The MDR phenotype in this pathogen was provided by Salmonella Genomic Island-1 (SGI-1), which confers protection against a wide range of antibiotics, including ampicillin (pse-1), chloramphenicol\/florfenicol (floR), streptomycin\/spectinomycin (aadA2), sulphonamides (sul1), and tetracycline (tetG) (ACSSuT).<\/li>\n<li>Further emergence of extensively drug-resistant (XDR) S. Typhimurium ST313 (having multi-drug resistant (MDR) and resistance against extended-spectrum beta-lactamase and azithromycin) in Africa posed a significant threat to global health.<\/li>\n<li>Recent studies reported an annual incidence of as many as 360 cases of typhoid fever per 1,00,000 people, with an annual estimate of 4.5 million cases and 8,930 deaths (0.2% fatality rate) in India.<\/li>\n<li>The continuous adaptation of this bacteria to the available antibiotics creates a risk of developing antimicrobial resistance in the future.<\/li>\n<li>The recent study showed that outer membrane porins of Salmonella Typhimurium play an essential role in the survival of the bacteria in the presence of antibiotics.<\/li>\n<\/ul>\n<h3><strong>Salmonella infection:<\/strong><\/h3>\n<ul>\n<li>It is a disease caused by the bacteria\u00a0Salmonella.<\/li>\n<li>Salmonella Typhimurium and salmonella typhi are two types of salmonella bacteria.\u00a0<\/li>\n<li>It is usually characterized by acute onset of fever, abdominal pain, diarrhoea, nausea and sometimes vomiting.<\/li>\n<li>Salmonella is 1 of 4 key global causes of diarrhoeal diseases.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr \/>\n<p><strong>Source :<\/strong><strong>\u00a0<\/strong><a href=\"https:\/\/epaper.thehindu.com\/Home\/ShareArticle?OrgId=GMUAEUDJL.1&amp;imageview=0\" target=\"_blank\" rel=\"nofollow noopener\">The Hindu<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Salmonella Tphimurium DT104 is a virulent pathogen for humans and animals, particularly cattle.<\/p>\n","protected":false},"author":5,"featured_media":8788,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-8787","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/8787","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=8787"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/8787\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/8788"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=8787"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=8787"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=8787"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}