{"id":89826,"date":"2026-02-25T14:01:21","date_gmt":"2026-02-25T08:31:21","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=89826"},"modified":"2026-02-25T14:01:21","modified_gmt":"2026-02-25T08:31:21","slug":"capsid","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/capsid\/","title":{"rendered":"Capsid"},"content":{"rendered":"<h2><b>Capsid Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">A new study found that to escape the drug Lenacapavir, HIV must damage its own capsid, reaffirming that the viral capsid is an effective target for antiviral therapy.<\/span><\/p>\n<h2><b>About Capsid<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">A capsid is a <\/span><b>three-dimensional proteinaceous capsular shell around a virus<\/b><span style=\"font-weight: 400;\"> that <\/span><b>encloses the viral genetic material.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It is located just <\/span><b>below the viral envelope<\/b><span style=\"font-weight: 400;\">.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The capsid is <\/span><b>made of several repeating<\/b><span style=\"font-weight: 400;\"> finite numbers of <\/span><b>protein subunits<\/b><span style=\"font-weight: 400;\"> known as <\/span><b>capsomeres or protomers.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The capsomeres of the protein coat can be associated with or may be closely related to the viral genetic material or nucleic acid.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The complexity of the capsid is dictated by the virus\u2019s own genetic material. The <\/span><b>more complex the genome<\/b><span style=\"font-weight: 400;\">, the <\/span><b>more intricate the protein shell must be<\/b><span style=\"font-weight: 400;\">.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><b>Some complex viruses have capsids with non-protein components like lipids<\/b><span style=\"font-weight: 400;\">, or in <\/span><b>certain viruses<\/b><span style=\"font-weight: 400;\">, the <\/span><b>capsid <\/b><span style=\"font-weight: 400;\">is further <\/span><b>enclosed in a glycoprotein layer;<\/b><span style=\"font-weight: 400;\"> such capsids are known as <\/span><b>enveloped capsids.<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">The viral capsid is in the <\/span><b>nanometer (nm) size range <\/b><span style=\"font-weight: 400;\">and possesses complex and unique mechanical properties.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">It serves <\/span><b>multiple functions,<\/b><span style=\"font-weight: 400;\"> namely, <\/span><b>encapsulating and protecting viral genetic material <\/b><span style=\"font-weight: 400;\">and <\/span><b>transferring of genetic material to the required place in the new host.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">For serving all these functions, the capsid needs <\/span><b>highly specific<\/b><span style=\"font-weight: 400;\"> mechanistic and <\/span><b>functional flexibility as well as strength.<\/b><\/li>\n<\/ul>\n<p><b>Source: <\/b><strong><a href=\"https:\/\/www.thehindu.com\/sci-tech\/science\/lenacapavir-study-confirms-hiv-capsid-as-drug-target-despite-resistance\/article70666577.ece\" target=\"_blank\" rel=\"nofollow noopener\">TH<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Capsid is a protein shell that protects viral genetic material and aids infection. A new study shows HIV must damage its capsid to resist Lenacapavir.<\/p>\n","protected":false},"author":23,"featured_media":89834,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[5707,21,23],"class_list":{"0":"post-89826","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-capsid","9":"tag-prelims-pointers","10":"tag-upsc-prelims-current-affairs","11":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/89826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=89826"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/89826\/revisions"}],"predecessor-version":[{"id":89877,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/89826\/revisions\/89877"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/89834"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=89826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=89826"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=89826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}