{"id":9261,"date":"2025-07-30T11:15:58","date_gmt":"2025-07-30T05:45:58","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=9261"},"modified":"2025-07-30T15:08:35","modified_gmt":"2025-07-30T09:38:35","slug":"what-is-n-nitrosodimethylamine-ndma","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/what-is-n-nitrosodimethylamine-ndma\/","title":{"rendered":"N-nitrosodimethylamine (NDMA)"},"content":{"rendered":"<h2><b>N-Nitrosodimethylamine (NDMA) Latest News<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Recently, drug regulator DCGI has asked drug controllers of all states and Union Territories to direct manufacturers under their jurisdiction to monitor the presence of a potentially carcinogenic chemical &#8212; N-Nitrosodimethylamine &#8212; in antacid Ranitidine.<\/span><\/p>\n<h2><b>About N-Nitrosodimethylamine<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>volatile organic chemical<\/b><span style=\"font-weight: 400;\"> that occurs widely in the environment due to its ready formation from commonly found precursors.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is classified as a <\/span><b>probable human carcinogen<\/b><span style=\"font-weight: 400;\"> (a substance that could cause cancer) on the basis of animal studies.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NDMA are formed when a <\/span><b>secondary or tertiary amine reacts<\/b><span style=\"font-weight: 400;\"> with a <\/span><b>nitrite ion<\/b><span style=\"font-weight: 400;\"> under acidic conditions.<\/span><\/li>\n<\/ul>\n<h2><b>Features of N-Nitrosodimethylamine<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is a <\/span><b>yellow, odorless liquid chemical<\/b><span style=\"font-weight: 400;\"> once used to make rocket fuel.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">It is also a byproduct of several manufacturing processes and water chlorination.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NDMA breaks down <\/span><b>when sunlight hits it.<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Applications:<\/b><span style=\"font-weight: 400;\"> Historically it was commercially used in the production of rocket fuel, antioxidants, softeners for copolymers, and additives for lubricants.<\/span><\/li>\n<\/ul>\n<h2><b>Exposure to N-Nitrosodimethylamine<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Normally, people are exposed to small amounts of NDMA in the environment and through food and water.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Chemicals found in food and water, such as nitrosamines or alkylamines, can turn into NDMA in the stomach.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NDMA is also <\/span><b>created when food or drink is processed<\/b><span style=\"font-weight: 400;\">. Foods such as cured meats (particularly bacon), beer, fish, cheese and even vegetables may contain NDMA.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Some people may have had exposure to NDMA through the use of contaminated medications<\/span><\/li>\n<\/ul>\n<p><b>Source:<\/b> <a href=\"https:\/\/economictimes.indiatimes.com\/industry\/healthcare\/biotech\/pharmaceuticals\/monitor-presence-of-potentially-carcinogenic-chemical-in-ranitidine-dcgi-to-drug-controllers\/articleshow\/122971132.cms?from=mdr\" target=\"_blank\" rel=\"nofollow noopener\"><span style=\"font-weight: 400;\">ET<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NDMA is a volatile organic chemical that occurs widely in the environment due to its ready formation from commonly found precursors. Read more about N-nitrosodimethylamine (NDMA), Meaning, Features, Exposure, Side Effects, Latest News<\/p>\n","protected":false},"author":5,"featured_media":57378,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[1892,21,22,23],"class_list":{"0":"post-9261","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-n-nitrosodimethylamine","9":"tag-prelims-pointers","10":"tag-upsc-current-affairs","11":"tag-upsc-prelims-current-affairs","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/9261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=9261"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/9261\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/57378"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=9261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=9261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=9261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}