{"id":98418,"date":"2026-04-15T12:49:38","date_gmt":"2026-04-15T07:19:38","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=98418"},"modified":"2026-04-16T14:25:57","modified_gmt":"2026-04-16T08:55:57","slug":"whole-exome-sequencing-wes","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/whole-exome-sequencing-wes\/","title":{"rendered":"Whole-Exome Sequencing (WES)"},"content":{"rendered":"<h2><b>Whole-Exome Sequencing (WES) Latest News<\/b><\/h2>\n<p style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Scientists recently used a genetic sequencing technique called whole exome sequencing to discover a new rare genetic disease.<\/span><\/p>\n<h2><b>About Whole-Exome Sequencing (WES)<\/b><\/h2>\n<ul>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">WES is the approach used to <\/span><b>sequence only the protein-coding regions<\/b><span style=\"font-weight: 400;\"> of the <\/span><b><a href=\"https:\/\/vajiramandravi.com\/current-affairs\/genome\/\" target=\"_blank\">human genome<\/a>.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">These <\/span><b>protein-coding regions<\/b><span style=\"font-weight: 400;\"> within the genome are <\/span><b>known as exons,<\/b><span style=\"font-weight: 400;\"> and they make up less than <\/span><b>2% of our entire genome,<\/b><span style=\"font-weight: 400;\"> but they are very important because they <\/span><b>contain about 85% of the genetic variants linked to different diseases.<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Together, <\/span><b>all the exons<\/b><span style=\"font-weight: 400;\"> in a genome are <\/span><b>known as the exome.<\/b><\/li>\n<li style=\"text-align: justify;\"><b>WES focuses on the exome<\/b><span style=\"font-weight: 400;\"> and provides a more <\/span><b>targeted approach compared to whole-genome sequencing (WGS)<\/b><span style=\"font-weight: 400;\">, which sequences the entire genome, including non-coding regions.\u00a0<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">Since most disease-related mutations are found in the exome, this makes WES an <\/span><b>effective tool for diagnosing genetic conditions <\/b><span style=\"font-weight: 400;\">and <\/span><b>understanding disease mechanisms.\u00a0<\/b><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">WES is a faster<\/span><b> and cost-effective <\/b><span style=\"font-weight: 400;\">alternative to WGS. It also <\/span><b>simplifies the data analysis <\/b><span style=\"font-weight: 400;\">process.<\/span><\/li>\n<li style=\"text-align: justify;\"><span style=\"font-weight: 400;\">WES is especially useful in research and clinical settings to i<\/span><b>dentify both common and rare genetic variants.<\/b><\/li>\n<\/ul>\n<p><strong>Source: <a href=\"https:\/\/www.news-medical.net\/news\/20260413\/Scientists-use-whole-exome-sequencing-to-discover-a-new-rare-genetic-disease.aspx\" target=\"_blank\" rel=\"nofollow noopener\">NM<\/a><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whole-Exome Sequencing (WES) is the approach used to sequence only the protein-coding regions of the human genome. Read more about Whole-Exome Sequencing (WES), Meaning, Latest News.<\/p>\n","protected":false},"author":23,"featured_media":98415,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[21,22,23,6870],"class_list":{"0":"post-98418","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"tag-prelims-pointers","9":"tag-upsc-current-affairs","10":"tag-upsc-prelims-current-affairs","11":"tag-wholeeexome-sequencing-wes","12":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/98418","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/23"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=98418"}],"version-history":[{"count":4,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/98418\/revisions"}],"predecessor-version":[{"id":98427,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/98418\/revisions\/98427"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/98415"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=98418"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=98418"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=98418"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}