{"id":9986,"date":"2023-04-23T06:56:46","date_gmt":"2023-04-23T01:26:46","guid":{"rendered":"https:\/\/vajiramandravi.com\/current-affairs\/?p=9986"},"modified":"2025-03-29T16:40:10","modified_gmt":"2025-03-29T11:10:10","slug":"what-are-aptamers","status":"publish","type":"post","link":"https:\/\/vajiramandravi.com\/current-affairs\/what-are-aptamers\/","title":{"rendered":"What are Aptamers?"},"content":{"rendered":"<h2><strong>About Aptamers:\u00a0<\/strong><\/h2>\n<ul>\n<li>They are short, single-stranded DNA or RNA (ssDNA or ssRNA) molecules that can selectively bind to a specific target, including proteins, peptides, carbohydrates, small molecules, toxins, and even live cells.<\/li>\n<li>Aptamers assume a variety of shapes due to their tendency to form helices and single-stranded loops.\u00a0<\/li>\n<li>They can be used as an antibody alternative in a variety of therapeutic, diagnostic, and target-binding applications.<\/li>\n<li>They can also be readily conjugated to gold nanoparticles or quantum dots as a basis for point-of-care diagnostics.<\/li>\n<li>Aptamers have been successfully used for the diagnosis and therapy of a broad spectrum of pathogens including bacteria, parasites, and viruses.<\/li>\n<\/ul>\n<h3><strong>What is a Biomarker?<\/strong><\/h3>\n<ul>\n<li>It is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease.\u00a0<\/li>\n<li>A biomarker may be used to see how well the body responds to a treatment for a disease or condition.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<hr \/>\n<h3><strong>Q1) What is RNA?<\/strong><\/h3>\n<p>RNA (Ribonucleic Acid) is a type of nucleic acid that is essential for the coding, decoding, regulation, and expression of genes. It is made up of a single strand of nucleotides, each consisting of a nitrogenous base (adenine, cytosine, guanine, or uracil), a five-carbon sugar (ribose), and a phosphate group.<\/p>\n<p><strong>Source:\u00a0<\/strong>\u00a0<a href=\"https:\/\/theprint.in\/science\/study-finds-antibody-substitutes-for-biosensing\/1527764\/\" target=\"_blank\" rel=\"nofollow noopener\"><u>Study finds antibody substitutes for biosensing<\/u><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Aptamers are short, single-stranded DNA or RNA molecules that can selectively bind to a specific target.<\/p>\n","protected":false},"author":5,"featured_media":9987,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":{"0":"post-9986","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-upsc-prelims-current-affairs","8":"no-featured-image-padding"},"acf":[],"_links":{"self":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/9986","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/comments?post=9986"}],"version-history":[{"count":0,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/posts\/9986\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media\/9987"}],"wp:attachment":[{"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/media?parent=9986"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/categories?post=9986"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vajiramandravi.com\/current-affairs\/wp-json\/wp\/v2\/tags?post=9986"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}