Aceclofenac
26-08-2023
11:24 AM
1 min read
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Overview:
Indian Veterinary Research Institute (IVRI) has recently demanded a ban on using aceclofenac in cattle after a new study showed that the drug metabolises into diclofenac in water buffaloes — as it does in cows.
About Aceclofenac:
- Aceclofenac is the prodrug of the non‐steroidal anti‐inflammatory drug (NSAID) diclofenac.
- Aceclofenac in water buffaloes poses the same threat to vultures as it is a pro-drug of diclofenac.
- Aceclofenac turns into diclofenac soon after it enters the livestock.
- Vulture Action Plan 2020-2025 also mentions the aceclofenac as ‘toxic’, along with other drugs like nimesulide and ketoprofen.
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Diclofenac:
- Diclofenac is an anti-inflammatory drug.
- It was banned for veterinary use by the Government of India in 2006.
- It was found to be the main cause of a dramatic decline (99 per cent) of the vulture population across Asia.
- The drug caused accidental poisoning in raptors after they fed on carcasses of cattle injected with it.
Source : Down to Earth