AlphaFold3

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Overview:

Google Deepmind has unveiled the third major version of its "AlphaFold" artificial intelligence model, designed to help scientists design drugs and target disease more effectively.

About AlphaFold3:

  • It is a new AI model developed by Google DeepMind and Isomorphic Labs. 
  • It is a revolutionary model that can predict the structure and interactions of all life’s molecules with unprecedented accuracy and even it mapped the behaviour for all of life's molecules, including human DNA.
  • It can generate molecules' joint 3D structure, revealing how they all fit together.
  • It models large biomolecules such as proteins, DNA and RNA, as well as small molecules, also known as ligands — a category encompassing many drugs.
  • Furthermore, AlphaFold 3 can model chemical modifications to these molecules which control the healthy functioning of cells, that when disrupted can lead to disease.
  • It assembles its predictions using a diffusion network, akin to those found in AI image generators. 
  • Significance
    • It allows scientists to see cellular systems in all their complexity, across structures, interactions and modifications.
    • This new window on the molecules of life reveals how they’re all connected and helps understand how those connections affect biological functions — such as the actions of drugs, the production of hormones and the health-preserving process of DNA repair.

Q1: What is DNA?

Deoxyribonucleic Acid (DNA) is a set of instructions found in a cell.These instructions are used for the growth and development of an organism. The DNA of a person is unique, and variation in the sequence of DNA can be used to match individuals and identify them.

Source: Google DeepMind unveils next generation of drug discovery AI model