Helicobacter pylori

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A two-step PCR-based assay of a small region of the Helicobacter pylori (H. pylori) bacteria can help detect H. pylori infection has been developed by a team of researchers from the National Institute of Cholera and Enteric Diseases (ICMR-NICED), Kolkata.

About Helicobacter pylori

  • It is a common type of bacteria that grows in the digestive tract and tends to attack the stomach lining. 
  • It is adapted to live in the harsh, acidic environment of the stomach. 
  • This infection usually happens during childhood. 
  • Its infections are usually harmless, but they’re responsible for most ulcers in the stomach and small intestine.
  • This bacterium can change the environment around it and reduce the acidity so it can survive more easily.
  • The spiral shape of H. pylori allows it to penetrate the stomach lining, where it’s protected by mucus and the body’s immune cells can’t reach it. 
  • Most people with H. pylori infection will never have any signs or symptoms. 
  • When signs or symptoms do occur with H. pylori infection, they are typically related to gastritis or a peptic ulcer and may include:
    • An ache or burning pain in your stomach (abdomen)
    • Stomach pain that may be worse when your stomach is empty
    • Nausea, Loss of appetite and unintentional weight loss etc.
  • Treatment
    • It typically involves a combination of antibiotics and a proton-pump inhibitor (a drug that reduces your stomach acid) for up to 14 days.
    • This treatment is sometimes referred to as triple therapy.

Q1) What is a Bacteria?

Bacteria are single-celled microorganisms that belong to the domain of prokaryotes. They are some of the most ancient and widespread forms of life on Earth, and they play a crucial role in various ecosystems and human life.

Source: NICED makes quick detection of drug-resistant H. pylori possible