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What is Nano-MIND Technology?

31-07-2024

09:13 AM

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1 min read
What is Nano-MIND Technology? Blog Image

Overview:

Researchers from the Korean Institute of Basic Science have developed a magnetogenetics technology dubbed Nano Magnetogenetic Interface for NeuroDynamics (Nano-MIND) which has been demonstrated on mice.

About Nano-MIND Technology:

  • Nano-MIND (Magnetogenetic Interface for NeuroDynamics) technology, opens up new possibilities for understanding and manipulating complex brain functions such as cognition, emotion, and motivation.
  • It allows for wireless, remote, and precise modulation of specific deep brain neural circuits using magnetism.
  • This innovative approach leverages magnetic fields and magnetized nanoparticles to selectively activate targeted brain circuits, offering a significant advancement over existing methods of brain manipulation.
  • Highlights of the research
    • The research team demonstrated the technology's capabilities by activating specific neurons in different brain regions of mice.
    • One notable achievement was the activation of inhibitory GABA receptors in the medial preoptic area (MPOA), which is responsible for maternal behaviours.
    • When these neurons were stimulated in non-maternal female mice, the animals exhibited significantly increased nurturing behaviours, mimicking those of maternal mice.
    • The researchers also successfully regulated feeding behaviours by targeting motivation circuits in the lateral hypothalamus.
  • Activation of inhibitory neurons in this area resulted in a remarkable 100% increase in appetite and feeding behaviours in mice. Conversely, when excitatory neurons were activated, the mice showed a more than 50% reduction in appetite and feeding behaviours.
  • Significance: It represents a significant step forward in neuroscience research and could have far-reaching implications for the development of brain-computer interfaces (BCIs) and the treatment of neurological disorders.

Q1: What are Neurons?

These are nerve cells that send messages all over your body to allow you to do everything from breathing to talking, eating, walking, and thinking.

Source: Scientists use magnetism to mind-control mice in world's first experiment