What is Nanopore Technology?

About Nanopore Technology: 

• Nanopore technology refers to nano-scale holes embedded in a thin membrane structure to detect the potential change when charged biological molecules smaller than nanopores pass through the hole.
• It has the potential to sense and analyze single-molecule amino acids, DNA, RNA, etc.
• It is a cutting-edge method for sequencing DNA and RNA by detecting changes in electrical conductivity as molecules pass through a nanopore.
  • In contrast to other sequencing technologies, nanopore‐based sequencing is cheaper, very easy to use, does not require much computational and lab infrastructure, and only needs a small amount of DNA in a test sample.
  • It is the only sequencing technology that offers real-time analysis in fully scalable formats, from pocket to population scale, that can analyze native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths.
  • It can also undertake targeted sequencing with a focus on specific genes/regions.

Q1: What is Nanotechnology?

It is the study and manipulation of matter at dimensions ranging from 1 to 100 nanometers, where unique phenomena allow for novel applications.

Source: Nanopores: A game-changer in early disease detection