Smart Insulin (NNC2215)

About Smart Insulin (NNC2215):

• The newly developed insulin named NNC2215 comprises two parts: a ring-shaped structure, and a molecule with a similar shape to glucose called a glucoside.
• How does it work?
  • When blood sugar levels are low, the glucoside binds to the ring, keeping the insulin in an inactive state to prevent further lowering of blood sugar.
  • But, as blood glucose rises, the glucoside is replaced by glucose itself, triggering the insulin to shift its shape and become active, helping bring blood sugar levels down to safer ranges.
• Researchers who developed NNC2215 found it to be as effective as human insulin at lowering blood glucose in rats and pigs. 

Diabetes

• Diabetes is a chronic disease that occurs when the pancreas can no longer make insulin, or the body cannot make good use of the insulin it produces.
• Insulin is a hormone that regulates blood glucose.
• Types of Diabetes
  • Type 1 diabetes: It often starts in childhood, occurs when the pancreas do not produce insulin (or enough insulin).
  • Type 2 diabetes: It results from the body’s ineffective use of insulin that it produces.
  • Gestational diabetes (GDM): It is a type of diabetes that consists of high blood glucose during pregnancy and is associated with complications for both mother and child. 

Q1:What is the Glycaemic Index?

Glycaemic Index ranks carbohydrate-containing foods based on the blood glucose response, post-prandial or after a meal. The higher the blood sugar reading, the higher will be the GI. It shows how quickly each food affects your blood sugar (glucose) level when that food is eaten on its own.

News: How ‘smart insulin’ promises to revolutionise diabetes treatment