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What is Crohn’s Disease?

08-12-2024

06:30 PM

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1 min read
What is Crohn’s Disease? Blog Image

Overview:

In a recent study published, researchers assess the efficacy and safety of filgotinib, a Janus kinase (JAK) 1 preferential inhibitor, as induction and maintenance therapy in patients with moderately to severely active Crohn's disease.

About Crohn’s Disease:

  • It is a type of inflammatory bowel disease (IBD).
  • It is a chronic, or long-term condition that causes inflammation in the digestive tract.
  • Causes: It is not clear what causes Crohn’s disease. Experts suggest that it may stem from an abnormal reaction of the immune system
  • Although it typically starts in childhood or early adulthood, Crohn’s disease can develop at any age.
  • Inflammation caused by Crohn's disease can involve different areas of the digestive tract in different people, most commonly the small intestine.
  • Symptoms: The most common symptoms of Crohn’s disease are diarrhoea, cramping and pain in your abdomen, anaemia, altered appetite, and weight loss. 
  • Treatment: There's no known cure for Crohn's disease, but therapies can greatly reduce its signs and symptoms.

Q1: What is filgotinib?

Filgotinib is a medication used primarily in the treatment of inflammatory conditions such as rheumatoid arthritis (RA), ulcerative colitis (UC), and Crohn's disease. It is classified as a Janus kinase (JAK) inhibitor, targeting specific pathways involved in the immune response.

News: Filgotinib offers new promise for managing Crohn’s disease