What is RoseTTAFold?

About RoseTTAFold:

• It is developed by researchers at the University Of Washington, U.S.
• It uses generative diffusion-based architectures (one kind of AI model) to predict structural complexes.
• The tools’ neural networks use massive amounts of input data to produce the desired output — the three-dimensional structures of proteins.
• It uses deep learning to quickly and accurately predict protein structures based on limited information. Without the aid of such software, it can take years of laboratory work to determine the structure of just one protein.
• It is a "three-track" neural network, meaning it simultaneously considers patterns in protein sequences, how a protein's amino acids interact with one another, and a protein's possible three-dimensional structure.

It has the capability to predict not just static structures of proteins and protein-protein interactions but also their ability to predict structures and interactions for any combination of protein, DNA, and RNA.

Q1: What are Peptides?

Peptides are chains of amino acids that are naturally found in the body. The amino acids in a peptide are connected to one another in a sequence by bonds called peptide bonds.

Source: The use of AI in drug development | Explained