Nonalcoholic Steatohepatitis (NASH)

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About Nonalcoholic Steatohepatitis (NASH)

It is liver inflammation and damage caused by a buildup of fat in the liver.
It is part of a group of conditions called nonalcoholic fatty liver disease.
NASH can get worse and cause scarring of the liver, which leads to cirrhosis. But the disease doesn’t always get worse.
It is similar to the kind of liver disease that is caused by long-term, heavy drinking. But NASH occurs in people who don’t abuse alcohol.
Symptoms: As NASH progresses and liver damage gets worse, you may start to have symptoms such as:
- Fatigue (feeling tired all the time).
- Weight loss for no clear reason.
- General weakness.
- An ache in the upper right part of your belly.
Causes: Things that put people at risk for NASH and for liver damage include: obesity, Insulin resistance and type 2 diabetes, high cholesterol and high triglycerides, metabolic syndrome etc.
Treatment for NASH includes managing conditions that increase your risk for NASH or make it worse. You can:
- Reduce your total cholesterol level.
- Reach a healthy weight. Losing 3% to 10% of your total body weight can make a difference.
- Control diabetes.

Q1) What is the function of liver?

The liver is a critical organ in the human body that is responsible for an array of functions that help support metabolism, immunity, digestion, detoxification, vitamin storage among other functions.

Source: First drug to treat common, lethal liver disease gets US nod