Crohn’s Disease

Crohn’s Disease Latest News

A detailed cellular study of Crohn’s disease recently mapped how gene activity changes across more than 50 cell types in the gut.

About Crohn’s Disease

• It is a chronic inflammatory bowel disease (IBD) that causes swelling and irritation of the tissues, called inflammation, in the digestive tract. 
• It can affect any part of your digestive tract, which runs from your mouth to your anus. But it usually affects the end of the small intestine and the beginning of the large intestine. 
• The inflammation often spreads into the deeper layers of the bowel.
• Crohn’s disease can be both painful and debilitating. Sometimes, it may lead to serious or life-threatening complications.

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Crohn’s Disease Causes

• Experts aren’t sure what causes Crohn’s disease but think genes, abnormal immune reactions, and the microbiome play a role.
• People with a first-degree relative, such as a parent, sibling, or child, are at higher risk to have the disease.  
• Crohn’s disease can develop at any age, but usually first appears in people aged in their 20s and 30s. 
• It is more common in people living in the Western world, but it’s also becoming more common in developing countries.  

Crohn’s Disease Symptoms

• The symptoms of Crohn’s disease can vary, depending on where and how severe your inflammation is. 
• The most common symptoms include:
  • Diarrhea.
  • Fever.
  • Fatigue.
  • Belly pain and cramping.
  • Blood in the stool.
  • Mouth sores.
  • Reduced appetite and weight loss.
  • Pain or drainage near or around the anus due to inflammation from a tunnel into the skin, called a fistula.
• These symptoms often come and go in cycles, called flares and remission.  

Crohn’s Disease Treatment

• Crohn’s is a lifelong condition. There’s no known cure for Crohn’s disease.
• But treatment can help you manage symptoms, reduce inflammation, and live an active life.

News: NM