India on U.S. Fentanyl Blacklist: Major’s List, Drug Trade, and U.S. Actions

India is on the U.S. fentanyl blacklist. Learn what the Major’s List is, fentanyl’s dangers, why regulation is tough, and how the U.S. is responding.

Fentanyl Blacklist

Fentanyl Blacklist Latest News

  • In the latest Major’s List sent to the U.S. Congress, President Donald Trump identified 23 countries, including India, Pakistan, China, and Afghanistan, as major sources or transit hubs for illicit drugs, particularly fentanyl, posing a threat to the U.S. and its citizens.

Understanding the Major’s List

  • The Major’s List, compiled annually, identifies countries where geography, trade, or industry enable significant narcotics or precursor chemical flows into global markets. 
  • Inclusion does not reflect counternarcotics performance but highlights drug production or transit roles. 
  • However, nations like Afghanistan, Bolivia, Myanmar, Colombia, and Venezuela were flagged as having “failed demonstrably” in meeting international drug-control obligations.

Fentanyl: A Deadly Synthetic Opioid

  • Fentanyl, a synthetic opioid developed in the 1960s for severe medical pain relief, is now the leading cause of overdose deaths in the U.S. 
  • Illicit fentanyl is nearly 50 times stronger than heroin, with just 2 mg proving fatal by suppressing brainstem respiratory centres. 
  • Between August 2023 and August 2024, over 57,000 Americans died from opioid overdoses, mostly fentanyl-related. 
  • Though overdoses can be reversed with naloxone, rapid administration is crucial to prevent brain injury or death. 
  • In 2022, the U.S. DEA seized enough fentanyl for 379 million lethal doses — enough to kill the nation’s entire population.

Why Regulating Fentanyl Is Difficult

  • Unlike plant-based drugs like heroin or cocaine, fentanyl is lab-made using chemical precursors such as N-phenethyl-4-piperidone (NPP) and 4-anilino-N-phenethylpiperidine (4-ANPP)
  • These compounds have legitimate industrial and pharmaceutical uses, making regulation tricky. 
  • In counterfeit labs, traffickers can convert these precursors into fentanyl with basic glassware, solvents, and moderate heat, using common organic chemistry reactions. 
  • Since small amounts of precursors yield large fentanyl quantities and can be discreetly shipped, controlling their diversion into illicit networks has proven extremely challenging.

Fentanyl Supply Chain and U.S. Response

  • The fentanyl trade is a complex network. China and India produce key precursor chemicals, some of which are diverted into illicit markets. 
  • Mexican cartels process these into fentanyl powder, later pressed into counterfeit pills or mixed with other drugs, and smuggled into the U.S., mainly through the southwest border.
  • The U.S. has pursued criminal prosecutions, trade penalties, and diplomatic pressure to curb trafficking. 
  • In January 2025, Indian firms Raxuter Chemicals and Athos Chemicals were charged with exporting fentanyl precursors. 
  • A senior executive of Raxuter was arrested in New York for smuggling. 
  • Following this, the U.S. Embassy in New Delhi revoked visas for business executives linked to trafficking.
  • In February 2025, the Trump administration imposed 25% tariffs on Canadian and Mexican imports and an additional 10% on Chinese imports, citing fentanyl trafficking. 
  • Tariffs on Canada and Mexico were suspended after stronger border enforcement, but those on China remain.

Domestic Enforcement and Public Health Measures

  • Within the U.S., the DEA has intensified seizures of fentanyl shipments, targeted trafficking networks, and intercepted counterfeit pills disguised as legitimate medicines. 
  • Simultaneously, naloxone distribution has been expanded, alongside public awareness campaigns warning against counterfeit drugs. 
  • Expanded treatment programmes aim to reduce demand and support recovery from opioid addiction.

Source: TH | IE | AJ

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Fentanyl blacklist FAQs

Q1. What is the U.S. Major’s List in drug control?+

Q2. Why has India been blacklisted on fentanyl?+

Q3. Why is fentanyl so dangerous compared to other opioids?+

Q4. Why is fentanyl regulation difficult globally?+

Q5. How is the U.S. combating fentanyl trafficking?+

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