Tetrodotoxin (TTX)

Suspected tetrodotoxin poisoning in Vizhinjam, Kerala raises food safety concerns. Learn about TTX sources, symptoms, toxicity, risks, and treatment options.

Tetrodotoxin
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Tetrodotoxin Latest News

Food safety authorities and doctors suspect that the severe illness in people who consumed seafood at a restaurant in Vizhinjam, Kerala, was caused by contamination with a highly potent marine neurotoxin, likely tetrodotoxin (TTX).

About Tetrodotoxin

  • It is an extremely potent marine neurotoxin.
  • It is a crystalline, weakly basic, colorless organic substance. It darkens above 220° C.
  • Chemical Formula: C11H17N3O8. 
  • It naturally occurs in the skin, intestine, and liver of some fish in the family Tetraodontidae. 
  • Examples include puffer fish, porcupine fish, ocean sunfish, and some species of newts and salamanders.
  • Human poisonings occur when the flesh and/or organs of the fish are improperly prepared and eaten. 
  • TTX interferes with the transmission of signals from nerves to muscles and causes an increasing paralysis of the muscles of the body. 
  • Its toxicity is more than 1000 times greater than sodium cyanide.
  • TTX poisoning can be fatal.
  • It has no known antidote. Treatment is mainly supportive.

Source: TH

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Tetrodotoxin FAQ's

Q1. What is Tetrodotoxin (TTX)?+

Q2. What are the physical characteristics of Tetrodotoxin?+

Q3. In which family of fish is Tetrodotoxin commonly found?+

Q4. How does Tetrodotoxin affect the human body?+

Q5. Is there a specific antidote for Tetrodotoxin poisoning?+

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