What is Abaucin?

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About Abaucin:

It is known to compromise the normal function of a protein called CCR2.
It appears to work by disrupting lipoprotein trafficking in A. baumannii.
Based on genetic studies, the researchers believe that abaucin could be preventing lipoprotein produced inside the bacteria from moving to the outer membrane.
Abaucin is also “species-selective”, it only disrupts the growth of A. baumannii, not other Gram-negative bacteria.

What is an Acinetobacter baumanni?

It is a Gram-negative bacteria, which means it has a protective outer membrane that allows it to resist antibiotics.
It has been associated with hospital-acquired infections in India.
It was acknowledged to be a “red alert” pathogen because of its exceptional ability to develop resistance to all currently available antibiotics.

Q1) What is Gram-negative bacteria?

Gram-negative bacteria are a group of bacteria that are characterized by their response to the Gram staining technique, which is a method used to classify bacteria into two broad categories: Gram-positive and Gram-negative. Gram-negative bacteria have a unique cell wall structure that distinguishes them from Gram-positive bacteria.

Source: Explained | Abaucin, the potential new antibiotic found with machine-learning