Question

UPSC Prelims 2016 Question:

In the context of the developments in Bioinformatics, the term ‘transcriptome’, sometimes seen in the news, refers to

  1. 1. a range of enzymes used in genome editing
  2. 2. the full range of mRNA molecules expressed by an organism
  3. 3. the description of the mechanism of gene expression
  4. 4. a mechanism of genetic mutations taking place in cells

Answer (Detailed Solution Below)

Option 2: the full range of mRNA molecules expressed by an organism

Detailed Solution

Explanation: 

  • The human genome is made up of DNA (deoxyribonucleic acid).  For the instructions to be carried out, DNA must be "read" and transcribed - in other words, copied - into RNA (ribonucleic acid). These gene readouts are called transcripts, and a transcriptome is a collection of all the gene readouts present in a cell.

  • There are various kinds of RNA. The major type, called messenger RNA (mRNA), plays a vital role in making proteins. In this process: mRNA is transcribed from genes. A transcriptome is the full range of messenger RNA (mRNA) molecules expressed by an organism. The term "transcriptome" can also be used to describe the array of mRNA transcripts produced in a particular cell or tissue type.

Therefore, option (2) is the correct answer.

Subject: Science & Technology | Biotechnology

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