N-Nitrosodimethylamine (NDMA) Latest News
Recently, drug regulator DCGI has asked drug controllers of all states and Union Territories to direct manufacturers under their jurisdiction to monitor the presence of a potentially carcinogenic chemical -- N-Nitrosodimethylamine -- in antacid Ranitidine.
About N-Nitrosodimethylamine
- It is a volatile organic chemical that occurs widely in the environment due to its ready formation from commonly found precursors.
- It is classified as a probable human carcinogen (a substance that could cause cancer) on the basis of animal studies.
- NDMA are formed when a secondary or tertiary amine reacts with a nitrite ion under acidic conditions.
Features of N-Nitrosodimethylamine
- It is a yellow, odorless liquid chemical once used to make rocket fuel.
- It is also a byproduct of several manufacturing processes and water chlorination.
- NDMA breaks down when sunlight hits it.
- Applications: Historically it was commercially used in the production of rocket fuel, antioxidants, softeners for copolymers, and additives for lubricants.
Exposure to N-Nitrosodimethylamine
- Normally, people are exposed to small amounts of NDMA in the environment and through food and water.
- Chemicals found in food and water, such as nitrosamines or alkylamines, can turn into NDMA in the stomach.
- NDMA is also created when food or drink is processed. Foods such as cured meats (particularly bacon), beer, fish, cheese and even vegetables may contain NDMA.
- Some people may have had exposure to NDMA through the use of contaminated medications
Source: ET
N-Nitrosodimethylamine (NDMA) FAQs
Q1: What are the side effects of N-Nitrosodimethylamine NDMA?
Ans: Acute (short-term) exposure to N-nitrosodimethylamine may damage the liver in humans, with symptoms that include nausea, vomiting, headaches, and malaise.
Q2: What foods contain NDMA?
Ans: NDMA can also be found in many processed foods and beverages such as whiskey, beer, cured meats, bacon, and cheeses.
